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NCT06692647 · ClinicalTrials.gov registry record · Phase 1
A Clinical Study of MK-4318 and Diltiazem in Healthy People (MK-4318-003)
A Phase 1 study, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 19
- Enrollment target
NCT06692647: Completed Phase 1 study, sponsored by Merck Sharp & Dohme.
NCT06692647 is a Phase 1 study that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 19 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06692647, a Phase 1 study, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 19 participants
- Enrollment target
Study Summary
The goal of this study is to learn what happens to MK-4318 in a person's body over time. Researchers will compare what happens to levels of MK-4318 in people's blood when it is taken with and without diltiazem. Researchers also want to learn about the safety of MK-4318 taken with and without diltiazem and if people tolerate them.
Primary Outcome
Blood samples will be collected to determine the AUC0-inf of MK-4318 in the presence of diltiazem.
Interventions
- DRUG Diltiazem
- DRUG MK-4318
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2024-02-09 |
| Est. Completion | 2024-04-11 |
| Phase | Phase 1 |
What the finished NCT06692647 record still lists
NCT06692647 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 19 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (68% lower).
The record links to 0 conditions, and to 2 interventions - of which Diltiazem is the first listed.
NCT06692647 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06692647 about?
NCT06692647 is a clinical study titled "A Clinical Study of MK-4318 and Diltiazem in Healthy People (MK-4318-003)". The goal of this study is to learn what happens to MK-4318 in a person's body over time. Researchers will compare what happens to levels of MK-4318 in people's blood when it is taken with and without diltiazem. Researchers also want to learn about the safety of MK-4318 taken with and without diltiaz...
What is the current status of trial NCT06692647?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 19 participants. The study started on 2024-02-09. Estimated completion is 2024-04-11.
What interventions are being tested in trial NCT06692647?
The interventions under investigation include: Diltiazem (DRUG), MK-4318 (DRUG).
Who is sponsoring clinical trial NCT06692647?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06692647's enrollment target sits among peer trials
19 1716th of 2000 higher than 281 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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