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NCT06684119 · ClinicalTrials.gov registry record · NA
Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)
A NA study of Pediatric Acute Respiratory Distress Syndrome, sponsored by Children's Hospital Los Angeles.
- Recruiting
- Registry status
- NA
- Development phase
- 60
- Enrollment target
- 1
- Study location
NCT06684119: Recruiting NA study of Pediatric Acute Respiratory Distress Syndrome, sponsored by Children's Hospital Los Angeles.
NCT06684119 is a NA study of Pediatric Acute Respiratory Distress Syndrome that is actively recruiting participants, run by Children's Hospital Los Angeles. The registered enrollment target is 60 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06684119, a NA study of Pediatric Acute Respiratory Distress Syndrome, is actively recruiting participants, sponsored by Children's Hospital Los Angeles.
- RECRUITING
- Registry status
- NA
- Development phase
- 60 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced. The primary and secondary aims of the study are as follows: Identify the difference between the optimal PEEP recommended by EIT metrics and the current guideline recommended approach to identifying optimal PEEP in PARDS. There will be a statistically significant difference in the recommended optimal PEEP identified using the EIT PEEP titration tool and that of the PEEP/FiO2 grid recommendations. Determine the difference in physiologic metrics between EIT optimal PEEP and the PEEP/FiO2 recommended PEEP. Participants will undergoing EIT monitoring while being subjected to PEEP titration protocol.
Primary Outcome
Collected using electrical impedence tomography (EIT). The EIT device provides the percentages of alveolar overdistention and collapse at each PEEP level. The best PEEP by EIT is defined as the PEEP level above the intersection of curves representing relative alveolar overdistention and collapse.
Conditions Studied
Interventions
- DEVICE Electrical Impedance Tomography positive end-expiratory pressure titration
Study Locations (1)
California
- Children's Hospital Los Angeles - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 60 participants |
| Start Date | 2024-12-10 |
| Est. Completion | 2027-07-01 |
| Phase | NA |
What NCT06684119 shows while recruiting
NCT06684119 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Pediatric Acute Respiratory Distress Syndrome appearing as the primary indexed condition, and to 1 intervention - of which Electrical Impedance Tomography positive end-expiratory pressure titration is the first listed.
NCT06684119 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06684119 about?
NCT06684119 is a clinical study titled "Pediatric Positive End Expiratory Pressure (PEEP) Titration Using Electrical Impedence Tomography (EIT)". The goal of this clinical trial is to perform a PEEP titration protocol and use EIT to identify the optimal PEEP at which lung overdistention and collapse are most effectively balanced. The primary and secondary aims of the study are as follows: Identify the difference between the optimal PEEP reco...
What is the current status of trial NCT06684119?
This trial is currently recruiting. It is a NA study. The enrollment target is 60 participants. The study started on 2024-12-10. Estimated completion is 2027-07-01.
What conditions does trial NCT06684119 study?
This clinical trial studies the following conditions: Pediatric Acute Respiratory Distress Syndrome.
What interventions are being tested in trial NCT06684119?
The interventions under investigation include: Electrical Impedance Tomography positive end-expiratory pressure titration (DEVICE).
Who is sponsoring clinical trial NCT06684119?
This trial is sponsored by Children's Hospital Los Angeles, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06684119 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06684119's enrollment target sits among peer trials
60 1164th of 2000 higher than 745 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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