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NCT06679413 · ClinicalTrials.gov registry record · Phase 1
A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants
A Phase 1 study, sponsored by UCB Biosciences.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT06679413: Completed Phase 1 study, sponsored by UCB Biosciences.
NCT06679413 is a Phase 1 study that has completed, run by UCB Biosciences. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06679413, a Phase 1 study, has completed, sponsored by UCB Biosciences.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
The purpose of the study is to assess the single-dose pharmacokinetics (PK) of 3 probe drugs (midazolam, bupropion, and metformin) before and after repeat doses of ZX008
Primary Outcome
Cmax is the maximum observed plasma concentration of Midazolam alone and in combination with ZX008 at steady state.
Interventions
- DRUG metformin
- DRUG midazolam
- DRUG bupropion
- DRUG fenfluramine HCl
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2024-12-04 |
| Est. Completion | 2025-06-12 |
| Phase | Phase 1 |
What the finished NCT06679413 record still lists
NCT06679413 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 4 interventions - of which metformin is the first listed.
NCT06679413 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06679413 about?
NCT06679413 is a clinical study titled "A Study to Assess Drug-drug Interaction of ZX008 in Healthy Male and Female Study Participants". The purpose of the study is to assess the single-dose pharmacokinetics (PK) of 3 probe drugs (midazolam, bupropion, and metformin) before and after repeat doses of ZX008
What is the current status of trial NCT06679413?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2024-12-04. Estimated completion is 2025-06-12.
What interventions are being tested in trial NCT06679413?
The interventions under investigation include: metformin (DRUG), midazolam (DRUG), bupropion (DRUG), fenfluramine HCl (DRUG).
Who is sponsoring clinical trial NCT06679413?
This trial is sponsored by UCB Biosciences, which has 39 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06679413's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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