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NCT06678880 · ClinicalTrials.gov registry record · NA
Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction
A NA study of Depression and Depression During the Menopausal Transition, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 120
- Enrollment target
- 1
- Study location
NCT06678880: Recruiting NA study of Depression and Depression During the Menopausal Transition, sponsored by University of California, San Diego.
NCT06678880 is a NA study of Depression and Depression During the Menopausal Transition that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 120 participants, below the 786-participant average among 679 other Depression trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06678880, a NA study of Depression and Depression During the Menopausal Transition, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 120 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn more about mood, sleep, and activity during menopause. The main question it aims to answer is: can mood and sleep dysfunction in menopause be improved by resetting misaligned circadian rhythm through one night of strategic sleep timing adjustment and two weeks of exposure to bright light at a certain time of day? Researchers will compare sleep timing (earlier vs. later) and bright white light exposure (morning or evening) to investigate the effect of melatonin levels on mood, sleep, and activity. Participants will 1) submit urine samples to measure melatonin levels, 2) be assigned to advance or delay their sleep for one night, 3) sit in front of a light box for 30 minutes per day (morning or evening) for 14 days, 4) complete questionnaires about their mood and sleep, and 5) wear a device that will measure their activity.
Primary Outcome
Collected to measure melatonin, a hormone that helps regulate your sleep and body clocks.
Conditions Studied
Interventions
- BEHAVIORAL Phase Advanced Intervention (PAI)
- BEHAVIORAL Phase Delay Intervention (PDI)
Study Locations (1)
California
- University of California San Diego Hillcrest Medical Center - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 120 participants |
| Start Date | 2025-03-11 |
| Est. Completion | 2029-02-28 |
| Phase | NA |
What NCT06678880 shows while recruiting
NCT06678880 is an interventional study that assigns participants to a tested intervention. The registered 120 participants enrollment target is mid-sized for trials with a published cap, below the 786-participant average among 679 other Depression trials with a reported enrollment target (85% lower).
The record links to 3 conditions, with Depression appearing as the primary indexed condition, and to 2 interventions - of which Phase Advanced Intervention (PAI) is the first listed.
NCT06678880 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06678880 about?
NCT06678880 is a clinical study titled "Sleep and Light Intervention (SALI) for Menopausal Mood Dysfunction". The goal of this clinical trial is to learn more about mood, sleep, and activity during menopause. The main question it aims to answer is: can mood and sleep dysfunction in menopause be improved by resetting misaligned circadian rhythm through one night of strategic sleep timing adjustment and two w...
What is the current status of trial NCT06678880?
This trial is currently recruiting. It is a NA study. The enrollment target is 120 participants. The study started on 2025-03-11. Estimated completion is 2029-02-28.
What conditions does trial NCT06678880 study?
This clinical trial studies the following conditions: Depression, Depression During the Menopausal Transition, Menopausal Depression.
What interventions are being tested in trial NCT06678880?
The interventions under investigation include: Phase Advanced Intervention (PAI) (BEHAVIORAL), Phase Delay Intervention (PDI) (BEHAVIORAL).
Who is sponsoring clinical trial NCT06678880?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06678880 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06678880's enrollment target sits among peer trials
120 292nd of 679 higher than 379 of 679 other Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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