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NCT06677996 · ClinicalTrials.gov registry record · Phase 1
A Phase 1 Study to Examine the Effects of Itraconazole After Single Dose Administration of Varegacestat (AL102) to Healthy Participants
A Phase 1 study, sponsored by Immunome.
- Completed
- Registry status
- Phase 1
- Development phase
- 22
- Enrollment target
NCT06677996: Completed Phase 1 study, sponsored by Immunome.
NCT06677996 is a Phase 1 study that has completed, run by Immunome. The registered enrollment target is 22 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06677996, a Phase 1 study, has completed, sponsored by Immunome.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 22 participants
- Enrollment target
Study Summary
This is an open label, fixed sequence, 1-way crossover drug-drug interaction (DDI) study in healthy participants.
Primary Outcome
AUC0-t for varegacestat administered with and without itraconazole.
Interventions
- DRUG varegacestat
- DRUG Itraconazole (200 mg)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2024-11-11 |
| Est. Completion | 2025-05-07 |
| Phase | Phase 1 |
What the finished NCT06677996 record still lists
NCT06677996 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (63% lower).
The record links to 0 conditions, and to 2 interventions - of which varegacestat is the first listed.
NCT06677996 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06677996 about?
NCT06677996 is a clinical study titled "A Phase 1 Study to Examine the Effects of Itraconazole After Single Dose Administration of Varegacestat (AL102) to Healthy Participants". This is an open label, fixed sequence, 1-way crossover drug-drug interaction (DDI) study in healthy participants.
What is the current status of trial NCT06677996?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 22 participants. The study started on 2024-11-11. Estimated completion is 2025-05-07.
What interventions are being tested in trial NCT06677996?
The interventions under investigation include: varegacestat (DRUG), Itraconazole (200 mg) (DRUG).
Who is sponsoring clinical trial NCT06677996?
This trial is sponsored by Immunome, which has 10 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06677996's enrollment target sits among peer trials
22 1601st of 2000 higher than 386 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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