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NCT06665633 · ClinicalTrials.gov registry record · Phase 1
Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy
A Phase 1 study, sponsored by Nova Southeastern University.
- Completed
- Registry status
- Phase 1
- Development phase
- 40
- Enrollment target
NCT06665633: Completed Phase 1 study, sponsored by Nova Southeastern University.
NCT06665633 is a Phase 1 study that has completed, run by Nova Southeastern University. The registered enrollment target is 40 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06665633, a Phase 1 study, has completed, sponsored by Nova Southeastern University.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 40 participants
- Enrollment target
Study Summary
Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the Veterans. The purpose of this pilot research study is to evaluate the effect of treating Veterans suffering from mTBI or persistent post-concussion syndrome with hyperbaric oxygen therapy (HBOT).
Primary Outcome
A brain SPECT scan is a type of imaging test that uses a radioactive substance and a special camera to create 3D pictures of the brain. It shows which areas of the brain are functioning the best or worst and how well the blood flows in the brain. The blood flow to the brain was measured pre- and post-HBOT. An infusion of a radioactive tracer, 30 millicurie (mCi) of Tc99m-Ceretec, was injected into the Veteran's IV site. The veteran was placed under the gamma scintillation camera (Siemens E-cam D
Interventions
- DRUG Oxygen 100 % Gas for Inhalation
- DEVICE Hyperbaric Oxygen Therapy Chamber
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2021-09-07 |
| Est. Completion | 2025-07-01 |
| Phase | Phase 1 |
What the finished NCT06665633 record still lists
NCT06665633 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (33% lower).
The record links to 0 conditions, and to 2 interventions - of which Oxygen 100 % Gas for Inhalation is the first listed.
NCT06665633 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06665633 about?
NCT06665633 is a clinical study titled "Treatment of U.S. Veterans With Mild Traumatic Brain Injury With Hyperbaric Oxygen Therapy". Mild traumatic brain (mTBI) injury affects 400,000 U.S. Veterans resulting in physical, cognitive and mental health symptoms. The Department of Defense (DoD) reported 26 suicides a day from mTBI despite ongoing care for the Veterans. The purpose of this pilot research study is to evaluate the effect...
What is the current status of trial NCT06665633?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2021-09-07. Estimated completion is 2025-07-01.
What interventions are being tested in trial NCT06665633?
The interventions under investigation include: Oxygen 100 % Gas for Inhalation (DRUG), Hyperbaric Oxygen Therapy Chamber (DEVICE).
Who is sponsoring clinical trial NCT06665633?
This trial is sponsored by Nova Southeastern University, which has 71 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06665633's enrollment target sits among peer trials
40 1130th of 2000 higher than 810 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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