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NCT06653400 · ClinicalTrials.gov registry record · Phase 1

Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy

A Phase 1 study of Analgesia and Abnormal Uterine Bleeding, sponsored by Icahn School of Medicine at Mount Sinai.

Recruiting
Registry status
Phase 1
Development phase
60
Enrollment target
1
Study location

NCT06653400: Recruiting Phase 1 study of Analgesia and Abnormal Uterine Bleeding, sponsored by Icahn School of Medicine at Mount Sinai.

NCT06653400 is a Phase 1 study of Analgesia and Abnormal Uterine Bleeding that is actively recruiting participants, run by Icahn School of Medicine at Mount Sinai. The registered enrollment target is 60 participants, below the 90-participant average among 19 other Analgesia trials with a reported enrollment target (33% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06653400, a Phase 1 study of Analgesia and Abnormal Uterine Bleeding, is actively recruiting participants, sponsored by Icahn School of Medicine at Mount Sinai.

RECRUITING
Registry status
Phase 1
Development phase
60 participants
Enrollment target
1
Study location

Study Summary

A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.

Primary Outcome

Pain as measured on a 100 mm visual analogue scale (VAS) with cervical dilation. Full scale scored from 0-100, higher score indicates more pain.

Interventions

  • DRUG Lidocaine
  • PROCEDURE paracervical block
  • DRUG ketorolac

Study Locations (1)

New York

  • Mount Sinai - New York

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-02-27
Est. Completion 2026-09-01
Phase Phase 1

What NCT06653400 shows while recruiting

NCT06653400 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 90-participant average among 19 other Analgesia trials with a reported enrollment target (33% lower).

The record links to 3 conditions, with Analgesia appearing as the primary indexed condition, and to 3 interventions - of which Lidocaine is the first listed.

NCT06653400 reports a single indexed study location in New York.

Frequently Asked Questions

What is clinical trial NCT06653400 about?

NCT06653400 is a clinical study titled "Combined Ketorolac and Lidocaine Paracervical Block for Office Hysteroscopy". A randomized double-blind placebo controlled trial comparing the effect of a combined ketorolac and lidocaine paracervical block with a standard lidocaine paracervical block on procedure related pain with office hysteroscopies.

What is the current status of trial NCT06653400?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 60 participants. The study started on 2025-02-27. Estimated completion is 2026-09-01.

What conditions does trial NCT06653400 study?

This clinical trial studies the following conditions: Analgesia, Abnormal Uterine Bleeding, Paracervical Block.

What interventions are being tested in trial NCT06653400?

The interventions under investigation include: Lidocaine (DRUG), paracervical block (PROCEDURE), ketorolac (DRUG).

Who is sponsoring clinical trial NCT06653400?

This trial is sponsored by Icahn School of Medicine at Mount Sinai, which has 708 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06653400 being conducted?

This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Analgesia

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06653400's enrollment target sits among peer trials

60 14th of 19 higher than 5 of 19 other Analgesia trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Analgesia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06653400, the US trial registry maintained by the National Library of Medicine. NCT06653400 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.