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NCT06648460 · ClinicalTrials.gov registry record · NA
Multimodal Differences in Effort-based Decision-Making in Depression
A NA study, sponsored by Georgia Institute of Technology.
- Not yet
- Registry status
- NA
- Development phase
- 90
- Enrollment target
NCT06648460 is a NA study that has not yet begun recruiting, run by Georgia Institute of Technology. The registered enrollment target is 90 participants.
The verdict
NCT06648460, a NA study, has not yet begun recruiting, sponsored by Georgia Institute of Technology.
- NOT YET RECRUITING
- Registry status
- NA
- Development phase
- 90 participants
- Enrollment target
Study Summary
Major depressive disorder (MDD) is a serious condition that causes long-term symptoms such as feeling sad, losing interest in activities, and having thoughts of self-harm. Difficulty in making an effort is a key factor in functional impairment. Current methods to evaluate this difficulty use clinical assessments and computer-based tasks, but there is a gap between the measurements and real-life behavior. To address this, the study team proposes creating an instrumented behavioral test, HORMES, to objectively assess reduced motivation during everyday activities and measure physiological responses. The study will examine differences in brain activity, autonomic system function, and metabolic energy expenditure in patients with major depression during a decision-making task that involves physical effort.
Interventions
- OTHER Effort-based Decision-Making Task
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 90 participants |
| Start Date | 2026-08-01 |
| Est. Completion | 2030-09-30 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06648460
The ClinicalTrials.gov registry entry for NCT06648460 describes a study currently listed as not yet recruiting, categorized as NA. The registered enrollment target is 90 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Georgia Institute of Technology, which has 24 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Effort-based Decision-Making Task is the first listed.
NCT06648460 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06648460 about?
NCT06648460 is a clinical study titled "Multimodal Differences in Effort-based Decision-Making in Depression". Major depressive disorder (MDD) is a serious condition that causes long-term symptoms such as feeling sad, losing interest in activities, and having thoughts of self-harm. Difficulty in making an effort is a key factor in functional impairment. Current methods to evaluate this difficulty use clinica...
What is the current status of trial NCT06648460?
This trial is currently not yet recruiting. It is a NA study. The enrollment target is 90 participants. The study started on 2026-08-01. Estimated completion is 2030-09-30.
What interventions are being tested in trial NCT06648460?
The interventions under investigation include: Effort-based Decision-Making Task (OTHER).
Who is sponsoring clinical trial NCT06648460?
This trial is sponsored by Georgia Institute of Technology, which has 24 total clinical trials registered on ClinicalTrials.gov.
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