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NCT06646731 · ClinicalTrials.gov registry record · NA
Cryoneurolysis for Painful Diabetic Neuropathy of the Foot
A NA study of Painful Diabetic Peripheral Neuropathy (PDPN), sponsored by University of California, San Diego.
- Recruiting
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT06646731 is a NA study of Painful Diabetic Peripheral Neuropathy (PDPN) that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 30 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06646731, a NA study of Painful Diabetic Peripheral Neuropathy (PDPN), is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
The study is a single-center, randomized, participant- and observer-masked, human-subjects, post-market clinical pilot study to investigate the use of ultrasound-guided percutaneous cryoneurolysis to treat diabetic neuropathy of the foot. A prolonged nerve block may be provided by freezing the nerve using a technique called "cryoneurolysis". With cryoneurolysis and ultrasound machines, a small needle-like "probe" may be placed through anesthetized skin and guided to the target nerve to allow freezing. The procedure takes about 6 minutes for each nerve, involves little discomfort, has no systemic side effects, and cannot be misused or become addictive. Participants will be randomly allocated to one of two possible treatments groups: cryoneurolysis (experimental) or sham (control). The primary outcome measure is the change in pain on the neuropathic pain scale from baseline 1 month following the procedure.
Conditions Studied
Interventions
- DEVICE cryoneurolysis
- DEVICE sham cryoneurolysis
Study Locations (1)
California
- University of California, San Diego - La Jolla
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-08-25 |
| Est. Completion | 2026-06 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06646731
The ClinicalTrials.gov registry entry for NCT06646731 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Diego, which has 775 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Painful Diabetic Peripheral Neuropathy (PDPN) appearing as the primary indexed condition, and to 2 interventions - of which cryoneurolysis is the first listed.
NCT06646731 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06646731 about?
NCT06646731 is a clinical study titled "Cryoneurolysis for Painful Diabetic Neuropathy of the Foot". The study is a single-center, randomized, participant- and observer-masked, human-subjects, post-market clinical pilot study to investigate the use of ultrasound-guided percutaneous cryoneurolysis to treat diabetic neuropathy of the foot. A prolonged nerve block may be provided by freezing the nerve...
What is the current status of trial NCT06646731?
This trial is currently recruiting. It is a NA study. The enrollment target is 30 participants. The study started on 2025-08-25. Estimated completion is 2026-06.
What conditions does trial NCT06646731 study?
This clinical trial studies the following conditions: Painful Diabetic Peripheral Neuropathy (PDPN).
What interventions are being tested in trial NCT06646731?
The interventions under investigation include: cryoneurolysis (DEVICE), sham cryoneurolysis (DEVICE).
Who is sponsoring clinical trial NCT06646731?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06646731 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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