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NCT06638879 · ClinicalTrials.gov registry record · Phase 1
Tacrolimus Toothpaste for Management of Oral Chronic Graft vs. Host Disease (cGVHD)
A Phase 1 study of Chronic Graft Versus Host Disease Oral, sponsored by Children's Hospital Medical Center, Cincinnati.
- Completed
- Registry status
- Phase 1
- Development phase
- 7
- Enrollment target
- 1
- Study location
NCT06638879 is a Phase 1 study of Chronic Graft Versus Host Disease Oral that has completed, run by Children's Hospital Medical Center, Cincinnati. The registered enrollment target is 7 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06638879, a Phase 1 study of Chronic Graft Versus Host Disease Oral, has completed, sponsored by Children's Hospital Medical Center, Cincinnati.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 7 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to investigate the use of a novel formulation of tacrolimus, as a toothpaste, in a population of patients with oral chronic graft vs. host disease (cGVHD) as an adjunctive therapy in addition to standard-of-care systemic therapy. The investigators plan to summarize our findings to add to the current body of literature regarding managing cGVHD, specifically those with oral involvement. Additionally, establishing effective topical application of tacrolimus in the oral cavity will allow for future prospective studies comparing outcomes for these patients with a more traditional standard of care.
Conditions Studied
Interventions
- DRUG Tacrolimus
Study Locations (1)
Ohio
- Cincinnati Children's Hospital Medical Center - Cincinnati
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 7 participants |
| Start Date | 2024-09-17 |
| Est. Completion | 2026-02-18 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06638879
The ClinicalTrials.gov registry entry for NCT06638879 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 7 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Children's Hospital Medical Center, Cincinnati, which has 571 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Chronic Graft Versus Host Disease Oral appearing as the primary indexed condition, and to 1 intervention - of which Tacrolimus is the first listed.
NCT06638879 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.
Frequently Asked Questions
What is clinical trial NCT06638879 about?
NCT06638879 is a clinical study titled "Tacrolimus Toothpaste for Management of Oral Chronic Graft vs. Host Disease (cGVHD)". This study aims to investigate the use of a novel formulation of tacrolimus, as a toothpaste, in a population of patients with oral chronic graft vs. host disease (cGVHD) as an adjunctive therapy in addition to standard-of-care systemic therapy. The investigators plan to summarize our findings to a...
What is the current status of trial NCT06638879?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 7 participants. The study started on 2024-09-17. Estimated completion is 2026-02-18.
What conditions does trial NCT06638879 study?
This clinical trial studies the following conditions: Chronic Graft Versus Host Disease Oral.
What interventions are being tested in trial NCT06638879?
The interventions under investigation include: Tacrolimus (DRUG).
Who is sponsoring clinical trial NCT06638879?
This trial is sponsored by Children's Hospital Medical Center, Cincinnati, which has 571 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06638879 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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