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NCT06638684 · ClinicalTrials.gov registry record · NA
T Cell Responses to Various Levels of Exercise Stress
A NA study of Healthy, sponsored by University of Kansas.
- Completed
- Registry status
- NA
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT06638684: Completed NA study of Healthy, sponsored by University of Kansas.
NCT06638684 is a NA study of Healthy that has completed, run by University of Kansas. The registered enrollment target is 16 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06638684, a NA study of Healthy, has completed, sponsored by University of Kansas.
- COMPLETED
- Registry status
- NA
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
The objective of this project is to quantify the immunoendocrine response to acute stress events combining both physical and psychological challenges. This work will serve as a pilot project examining differential stress induction in response to exercise. Participants will have an instructor with prior military training lead a two-hour training session for 10 recreationally fit male volunteers. You will be randomly assigned to a high-intensity training group to participate in the "military style" training and a low-intensity training group who will participate in a low-intensity cardiovascular training protocol. Blood samples will be collected from you prior to and following the exercise session and these samples will be analyzed for endocrine measures as well as markers of immune function to include chemokines and cytokines.
Primary Outcome
Blood samples were collected using standard venipuncture technique. Blood samples were obtained at baseline, immediately post-exercise (0h), 1 hour post (1h), 4 hours (4h), and 6 hours (6h) post-exercise in heparin vacutainer tubes. Peripheral blood mononuclear cells (PBMC) were isolated using Ficoll-Paque PLUS density gradient centrifugation. Total T cells were purified from washed PBMC by E-rosetting. T cell proliferation was analyzed in response to co-stimulation through CD3+CD28 using plate-
Conditions Studied
Interventions
- OTHER Exercise
Study Locations (1)
Kansas
- University of Kansas - Lawrence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2015-02-20 |
| Est. Completion | 2016-05-12 |
| Phase | NA |
What the finished NCT06638684 record still lists
NCT06638684 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT06638684 reports a single indexed study location in Kansas.
Frequently Asked Questions
What is clinical trial NCT06638684 about?
NCT06638684 is a clinical study titled "T Cell Responses to Various Levels of Exercise Stress". The objective of this project is to quantify the immunoendocrine response to acute stress events combining both physical and psychological challenges. This work will serve as a pilot project examining differential stress induction in response to exercise. Participants will have an instructor with pr...
What is the current status of trial NCT06638684?
This trial is currently completed. It is a NA study. The enrollment target is 16 participants. The study started on 2015-02-20. Estimated completion is 2016-05-12.
What conditions does trial NCT06638684 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT06638684?
The interventions under investigation include: Exercise (OTHER).
Who is sponsoring clinical trial NCT06638684?
This trial is sponsored by University of Kansas, which has 66 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06638684 being conducted?
This trial has 1 study location across Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT06638684's enrollment target sits among peer trials
16 936th of 1090 higher than 137 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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