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Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors
NCT06598800 · View on ClinicalTrials.gov ↗
Study Summary
This is a first-in-human (FIH), Phase 1a/1b, open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-T187 alone and in combination with other therapeutic agents in participants with advanced solid tumors.
Conditions Studied
Interventions
- DRUG Drug: BG-T187
- DRUG Other Therapeutic Agents
Study Locations (20)
New South Wales
- Blacktown Cancer and Haematology Centre — Blacktown
- Macquarie University — North Ryde
Hubei
- Tongji Hospital of Tongji Medical College Huazhong University of Science and Technology — Wuhan
- Hubei Cancer Hospital — Wuhan
New Jersey
- Hackensack University Medical Center — Hackensack
Texas
- The University of Texas Md Anderson Cancer Center — Houston
Virginia
- Next Virginia — Fairfax
Wisconsin
- Washington University, St Louis, Division of Oncology — Madison
Victoria
- Cabrini Hospital Malvern — Malvern East
Western Australia
- Linear Clinical Research — Nedlands
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 87 participants |
| Start Date | 2024-10-18 |
| Est. Completion | 2028-09-30 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06598800
The ClinicalTrials.gov registry entry for NCT06598800 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 87 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is BeiGene, which has 91 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Advanced Solid Tumor appearing as the primary indexed condition, and to 2 interventions — of which Drug: BG-T187 is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06598800 reports 20 study locations spanning 18 distinct geographic areas — top geographies include New South Wales, Hubei, New Jersey. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06598800 about?
NCT06598800 is a clinical study titled "Study of BG-T187 Alone and in Combination With Other Therapeutic Agents in Participants With Advanced Solid Tumors". This is a first-in-human (FIH), Phase 1a/1b, open-label, multicenter, dose escalation and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics, and preliminary antitumor activity of BG-T187 alone and in combination with other therapeutic agents in partic...
What is the current status of trial NCT06598800?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 87 participants. The study started on 2024-10-18. Estimated completion is 2028-09-30.
What conditions does trial NCT06598800 study?
This clinical trial studies the following conditions: Advanced Solid Tumor. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06598800?
The interventions under investigation include: Drug: BG-T187 (DRUG), Other Therapeutic Agents (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06598800?
This trial is sponsored by BeiGene, which has 91 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06598800 being conducted?
This trial has 20 study locations across New Jersey, Texas, Virginia, Wisconsin, New South Wales. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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