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Safety and Efficacy of a Drug Eluting Slim Modiolar Electrode Array
NCT06598059 · View on ClinicalTrials.gov ↗
Study Summary
This clinical study will test a new type of cochlear implant known as CI632D. This experimental cochlear implant has been designed to slowly release a drug called dexamethasone. Dexamethasone works to ease inflammation and reduce tissue injury, which is common after any type of surgery. The goal is to learn if the dexamethasone in the CI632D implant lessens these reactions inside the ear following surgery and if this makes the implant work as well, or even better, in improving hearing than what would be expected with a standard cochlear implant. The study will be conducted in adults with sensorineural hearing loss, a type of hearing loss caused by damage to the inner ear or auditory nerve (the nerve that carries sound signals from the ear to the brain). The study participants will receive the CI632D experimental implant and will complete tests to see how well they are hearing and how well the implant is working.
Conditions Studied
Interventions
- DRUG Dexamethasone
- DEVICE Cochlear implant
Study Locations (11)
New York
- New York Eye and Ear Infirmary — New York
- NYU Langone Health — New York
- Northwell Health Long Island Jewish Medical Center — New York
California
- UCLA Medical Center — Los Angeles
Colorado
- Rocky Mountain Ear Center — Englewood
Iowa
- University of Iowa — Iowa City
Michigan
- Henry Ford Health — Detroit
Missouri
- Washington University — St Louis
Ohio
- University Hospitals — Cleveland
Oregon
- Oregon Health & Science University — Portland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 56 participants |
| Start Date | 2025-01-03 |
| Est. Completion | 2026-09 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06598059
The ClinicalTrials.gov registry entry for NCT06598059 describes a study currently listed as active not recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 56 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cochlear, which has 43 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Hearing Loss appearing as the primary indexed condition, and to 2 interventions — of which Dexamethasone is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06598059 reports 11 study locations spanning 9 distinct geographic areas — top geographies include New York, California, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06598059 about?
NCT06598059 is a clinical study titled "Safety and Efficacy of a Drug Eluting Slim Modiolar Electrode Array". This clinical study will test a new type of cochlear implant known as CI632D. This experimental cochlear implant has been designed to slowly release a drug called dexamethasone. Dexamethasone works to ease inflammation and reduce tissue injury, which is common after any type of surgery. The goal is ...
What is the current status of trial NCT06598059?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 56 participants. The study started on 2025-01-03. Estimated completion is 2026-09.
What conditions does trial NCT06598059 study?
This clinical trial studies the following conditions: Hearing Loss. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06598059?
The interventions under investigation include: Dexamethasone (DRUG), Cochlear implant (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06598059?
This trial is sponsored by Cochlear, which has 43 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06598059 being conducted?
This trial has 11 study locations across California, Colorado, Iowa, Michigan, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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