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NCT06593457 · ClinicalTrials.gov registry record · Phase 1
A Food-Effect, Drug-Drug Interaction, and Pharmacokinetics Study of NX-5948 in Healthy Adult Subjects
A Phase 1 study, sponsored by Nurix Therapeutics.
- Completed
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT06593457: Completed Phase 1 study, sponsored by Nurix Therapeutics.
NCT06593457 is a Phase 1 study that has completed, run by Nurix Therapeutics. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06593457, a Phase 1 study, has completed, sponsored by Nurix Therapeutics.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
This is a Phase 1, 2-part double-blinded (with respect to NX-5948/placebo), placebo-controlled study. Part 1 is a randomized, 3 period cross-over food-effect (FE) and drug-drug interaction (DDI) study. Part 2 is a single-period PK evaluation study.
Primary Outcome
To evaluate the effect of food on the single-dose pharmacokinetics (PK) of NX-5948 in healthy subjects.
Interventions
- DRUG Matching Placebo
- DRUG IP
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2024-08-20 |
| Est. Completion | 2024-11-14 |
| Phase | Phase 1 |
What the finished NCT06593457 record still lists
NCT06593457 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 2 interventions - of which Matching Placebo is the first listed.
NCT06593457 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06593457 about?
NCT06593457 is a clinical study titled "A Food-Effect, Drug-Drug Interaction, and Pharmacokinetics Study of NX-5948 in Healthy Adult Subjects". This is a Phase 1, 2-part double-blinded (with respect to NX-5948/placebo), placebo-controlled study. Part 1 is a randomized, 3 period cross-over food-effect (FE) and drug-drug interaction (DDI) study. Part 2 is a single-period PK evaluation study.
What is the current status of trial NCT06593457?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2024-08-20. Estimated completion is 2024-11-14.
What interventions are being tested in trial NCT06593457?
The interventions under investigation include: Matching Placebo (DRUG), IP (DRUG).
Who is sponsoring clinical trial NCT06593457?
This trial is sponsored by Nurix Therapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06593457's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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