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Endoscopic Ultrasound Shear Wave Elastography Study
NCT06592820 · View on ClinicalTrials.gov ↗
Study Summary
This study shall be a prospective, multicenter, single arm, consecutive, interventional study conducted in a post-market setting using commercially available devices. Consecutive, eligible patients with clinical suspicion of MASLD or MASH reporting for an endoscopic ultrasound and liver biopsy for evaluation of fibrosis will be enrolled. EUS Shear Wave Elastography and Attenuation Imaging technologies will be compared to liver biopsy and FibroScan results and other non-invasive fibrosis screening modalities . The data collected during this study will be evaluated in accordance with the procedures set forth in the protocol. The main question\[s\] it aims to answer are: * Establish optimal cutoffs for EUS-SWE in reference to liver biopsies staging system for liver fibrosis * Evaluate the diagnostic performance of EUS-SWE compared to FibroScan (VCTE) and to other non-invasive fibrosis screening modalities (screening scores). Participants will undergo: * Endoscopic Ultrasound with Shear Wave Elastography (SWE) and Attenuation Imaging (ATI) * Liver biopsy * FibroScan
Conditions Studied
Interventions
- DEVICE Endoscopic Ultrasound Shear Wave Elastography (EUS) and Attenuation Imaging
- DEVICE FibroScan
- DEVICE Liver biopsy
Study Locations (2)
Massachusetts
- Brigham and Women's Hospital — Boston
Pennsylvania
- Geisinger Medical Center — Danville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 300 participants |
| Start Date | 2025-09-03 |
| Est. Completion | 2027-03-28 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06592820
The ClinicalTrials.gov registry entry for NCT06592820 describes a study currently listed as recruiting. It is categorized as an unspecified phase, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 300 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Olympus Corporation of the Americas, which has 4 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 4 conditions, with MASLD appearing as the primary indexed condition, and to 3 interventions — of which Endoscopic Ultrasound Shear Wave Elastography (EUS) and Attenuation Imaging is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06592820 reports 2 study locations spanning 2 distinct geographic areas — top geographies include Massachusetts, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06592820 about?
NCT06592820 is a clinical study titled "Endoscopic Ultrasound Shear Wave Elastography Study". This study shall be a prospective, multicenter, single arm, consecutive, interventional study conducted in a post-market setting using commercially available devices. Consecutive, eligible patients with clinical suspicion of MASLD or MASH reporting for an endoscopic ultrasound and liver biopsy for e...
What is the current status of trial NCT06592820?
This trial is currently recruiting. The enrollment target is 300 participants. The study started on 2025-09-03. Estimated completion is 2027-03-28.
What conditions does trial NCT06592820 study?
This clinical trial studies the following conditions: MASLD, Fibrosis, Liver, Chronic Liver Disease, MASH. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06592820?
The interventions under investigation include: Endoscopic Ultrasound Shear Wave Elastography (EUS) and Attenuation Imaging (DEVICE), FibroScan (DEVICE), Liver biopsy (DEVICE). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06592820?
This trial is sponsored by Olympus Corporation of the Americas, which has 4 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06592820 being conducted?
This trial has 2 study locations across Massachusetts, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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