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NCT06586671 · ClinicalTrials.gov registry record · Phase 1

A Study to Compare Forms of Nemtabrutinib (MK-1026) in Healthy Adult Participants (MK-1026-007)

A Phase 1 study of Hematological Malignancy, sponsored by Merck Sharp & Dohme.

Completed
Registry status
Phase 1
Development phase
40
Enrollment target
1
Study location

NCT06586671: Completed Phase 1 study of Hematological Malignancy, sponsored by Merck Sharp & Dohme.

NCT06586671 is a Phase 1 study of Hematological Malignancy that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 40 participants, below the 117-participant average among 9 other Hematological Malignancy trials with a reported enrollment target (66% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06586671, a Phase 1 study of Hematological Malignancy, has completed, sponsored by Merck Sharp & Dohme.

COMPLETED
Registry status
Phase 1
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

The goal of the study is to measure and compare the levels of nemtabrutinib in the blood after taking different forms of nemtabrutinib orally on an empty stomach (fasted) to see if they are the same or different.

Primary Outcome

Blood samples will be collected to determine the AUC0-inf of nemtabrutinib.

Conditions Studied

Interventions

  • DRUG Nemtabrutinib

Study Locations (1)

Florida

  • QPS-MRA, LLC-Early Phase (Site 0002) - South Miami

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2023-08-28
Est. Completion 2023-11-13
Phase Phase 1
Merck Sharp & Dohme

558 total trials

What the finished NCT06586671 record still lists

NCT06586671 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 117-participant average among 9 other Hematological Malignancy trials with a reported enrollment target (66% lower).

The record links to 1 condition, with Hematological Malignancy appearing as the primary indexed condition, and to 1 intervention - of which Nemtabrutinib is the first listed.

NCT06586671 reports a single indexed study location in Florida.

Frequently Asked Questions

What is clinical trial NCT06586671 about?

NCT06586671 is a clinical study titled "A Study to Compare Forms of Nemtabrutinib (MK-1026) in Healthy Adult Participants (MK-1026-007)". The goal of the study is to measure and compare the levels of nemtabrutinib in the blood after taking different forms of nemtabrutinib orally on an empty stomach (fasted) to see if they are the same or different.

What is the current status of trial NCT06586671?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2023-08-28. Estimated completion is 2023-11-13.

What conditions does trial NCT06586671 study?

This clinical trial studies the following conditions: Hematological Malignancy.

What interventions are being tested in trial NCT06586671?

The interventions under investigation include: Nemtabrutinib (DRUG).

Who is sponsoring clinical trial NCT06586671?

This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06586671 being conducted?

This trial has 1 study location across Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Hematological Malignancy

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT06586671's enrollment target sits among peer trials

40 7th of 9 higher than 3 of 9 other Hematological Malignancy trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Hematological Malignancy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT06586671, the US trial registry maintained by the National Library of Medicine. NCT06586671 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.