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Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
NCT06567743 · View on ClinicalTrials.gov ↗
Study Summary
This is a Phase 2, Multi-Arm, Multi-Cohort, Open-Label Study to Evaluate the Safety and Efficacy of Cretostimogene Grenadenorepvec in Participants with High-Risk Non-Muscle-Invasive Bladder Cancer.
Conditions Studied
Interventions
- DRUG Cretostimogene Grenadenorepvec
Study Locations (20)
California
- Michael G Oefelein, MD Clinical Trials — Bakersfield
- Genesis Research (Greater Los Angeles) — Los Alamitos
- Advanced Urology — Los Angeles
- Urology Center of Southern California — Murrieta
- University of California, Irvine — Orange
- Om research — San Diego
- University of Southern California — San Diego
- Genesis Research (Greater Los Angeles) — Torrance
Florida
- University of Florida — Gainesville
- Mayo Clinic Florida — Jacksonville
- Advanced Urology Institute (Solaris) — Largo
- Advanced Urology Institute — Oxford
- Advanced Urology Institute - Tallahassee (Solaris) — Tallahassee
Arizona
- Mayo Clinic Arizona — Phoenix
- Arizona Urology Specialty — Tucson
Arkansas
- University of Arkansas for Medical Sciences — Little Rock
- Arkansas Urology — Little Rock
Colorado
- Colorado Urology — Lakewood
- Urology Associates, Lone Tree — Lone Tree
Georgia
- Emory University — Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 325 participants |
| Start Date | 2024-09-16 |
| Est. Completion | 2027-12-30 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06567743
The ClinicalTrials.gov registry entry for NCT06567743 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 325 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is CG Oncology, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with High-Risk Non-Muscle-Invasive Bladder Cancer appearing as the primary indexed condition, and to 1 intervention — of which Cretostimogene Grenadenorepvec is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT06567743 reports 20 study locations spanning 6 distinct geographic areas — top geographies include California, Florida, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT06567743 about?
NCT06567743 is a clinical study titled "Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC". This is a Phase 2, Multi-Arm, Multi-Cohort, Open-Label Study to Evaluate the Safety and Efficacy of Cretostimogene Grenadenorepvec in Participants with High-Risk Non-Muscle-Invasive Bladder Cancer.
What is the current status of trial NCT06567743?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 325 participants. The study started on 2024-09-16. Estimated completion is 2027-12-30.
What conditions does trial NCT06567743 study?
This clinical trial studies the following conditions: High-Risk Non-Muscle-Invasive Bladder Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT06567743?
The interventions under investigation include: Cretostimogene Grenadenorepvec (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT06567743?
This trial is sponsored by CG Oncology, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT06567743 being conducted?
This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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