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NCT06561386 · ClinicalTrials.gov registry record · Phase 3
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%
A Phase 3 study of Non-Small Cell Lung Cancer, sponsored by Bristol-Myers Squibb.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 1,000
- Enrollment target
- 20
- Study locations
NCT06561386 is a Phase 3 study of Non-Small Cell Lung Cancer that is actively recruiting participants, run by Bristol-Myers Squibb. The registered enrollment target is 1,000 participants, above the 657-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (52% higher). The trial reports 20 study locations across 12 states.
The verdict
NCT06561386, a Phase 3 study of Non-Small Cell Lung Cancer, is actively recruiting participants, sponsored by Bristol-Myers Squibb.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
The purpose of this study is to compare the efficacy of Nivolumab and Relatlimab in combination with chemotherapy to Pembrolizumab with Chemotherapy in participants with stage IV or recurrent Non-squamous Non-small Cell Lung Cancer with PD-L1 expression ≥ 1%
Conditions Studied
Interventions
- DRUG Pembrolizumab
- DRUG Carboplatin
- DRUG Pemetrexed
- DRUG Nivolumab
- DRUG Relatlimab
Study Locations (20)
California
- Local Institution - 0112 - Los Angeles
- University of California Davis (UC Davis) Comprehensive Cancer Center - Sacramento
- San Francisco Oncology Associates - San Francisco
- UCLA Hematology/Oncology - Santa Monica - Santa Monica
Florida
- University of Miami Hospital and Clinics, Sylvester Cancer Center - Miami
- Memorial Hospital West - Pembroke Pines
- Florida Cancer Specialists - North - St. Petersburg
- Florida Cancer Specialists - East - West Palm Beach
Kentucky
- Saint Elizabeth Medical Center Edgewood - Edgewood
- Local Institution - 0130 - Lexington
New York
- Local Institution - 0356 - Hawthorne
- Veterans Affairs New York Harbor Healthcare System - New York
Arizona
- Southern Arizona VA Health Care System - Tucson
Illinois
- Affiliated Oncologists, LLC - Chicago Ridge
Kansas
- Local Institution - 0251 - Wichita
Mississippi
- Hattiesburg Clinic Hematology/Oncology - Hattiesburg
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,000 participants |
| Start Date | 2024-10-07 |
| Est. Completion | 2032-08-04 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06561386
The ClinicalTrials.gov registry entry for NCT06561386 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 1,000 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 657-participant average among 449 other Non-Small Cell Lung Cancer trials with a reported enrollment target (52% higher). The listed sponsor is Bristol-Myers Squibb, which has 1,025 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Non-Small Cell Lung Cancer appearing as the primary indexed condition, and to 5 interventions - of which Pembrolizumab is the first listed.
NCT06561386 reports 20 study locations spanning 12 distinct geographic areas - top geographies include California, Florida, Kentucky.
Frequently Asked Questions
What is clinical trial NCT06561386 about?
NCT06561386 is a clinical study titled "A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression ≥ 1%". The purpose of this study is to compare the efficacy of Nivolumab and Relatlimab in combination with chemotherapy to Pembrolizumab with Chemotherapy in participants with stage IV or recurrent Non-squamous Non-small Cell Lung Cancer with PD-L1 expression ≥ 1%
What is the current status of trial NCT06561386?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 1,000 participants. The study started on 2024-10-07. Estimated completion is 2032-08-04.
What conditions does trial NCT06561386 study?
This clinical trial studies the following conditions: Non-Small Cell Lung Cancer.
What interventions are being tested in trial NCT06561386?
The interventions under investigation include: Pembrolizumab (DRUG), Carboplatin (DRUG), Pemetrexed (DRUG), Nivolumab (DRUG), Relatlimab (DRUG).
Who is sponsoring clinical trial NCT06561386?
This trial is sponsored by Bristol-Myers Squibb, which has 1,025 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06561386 being conducted?
This trial has 20 study locations across Arizona, California, Florida, Illinois, Kansas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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