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NCT06556095 · ClinicalTrials.gov registry record · Early Phase 1
Ridge Preservation With FDBA (Freeze Dried Bone Allograft) Using Dexamethasone vs. Saline
A Early Phase 1 study, sponsored by The University of Texas Health Science Center at San Antonio.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 44
- Enrollment target
NCT06556095: Completed Early Phase 1 study, sponsored by The University of Texas Health Science Center at San Antonio.
NCT06556095 is a Early Phase 1 study that has completed, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 44 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (17% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06556095, a Early Phase 1 study, has completed, sponsored by The University of Texas Health Science Center at San Antonio.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 44 participants
- Enrollment target
Study Summary
Following the removal of a tooth, a bone graft is often placed in the socket to try to maintain the volume of bone that was there when the tooth was present so that the bone does not "shrink". The bone graft is kept in place with a small piece of material over the top of the tooth socket and with stitches. This procedure is called "Ridge Preservation". Many different materials are used for ridge preservation, including bone allografts (bone grafts derived from a human tissue donor). These bone allografts are dehydrated (dried) during processing. Before using the material in the socket, the material is re-hydrated (wetted). The most common hydrating (wetting) agent is normal saline (sterile salt water), but other hydrating agents such as blood can also be used. The bone allograft used in this study is Food and Drug Administration (FDA) approved.
Primary Outcome
Difference in percentage of new bone formation at 16 weeks (±2 weeks) after ridge preservation is performed using a combination freeze-dried bone allograft (70% mineralized FDBA:30% demineralized FDBA) that is hydrated for 5 minutes in either sterile saline (control group) or a 4mg/ml dexamethasone solution (test group).
Interventions
- DRUG Dexamethasone 4mg/ml solution
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2024-09-16 |
| Est. Completion | 2026-01-08 |
| Phase | Early Phase 1 |
What the finished NCT06556095 record still lists
NCT06556095 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (17% lower).
The record links to 0 conditions, and to 1 intervention - of which Dexamethasone 4mg/ml solution is the first listed.
NCT06556095 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06556095 about?
NCT06556095 is a clinical study titled "Ridge Preservation With FDBA (Freeze Dried Bone Allograft) Using Dexamethasone vs. Saline". Following the removal of a tooth, a bone graft is often placed in the socket to try to maintain the volume of bone that was there when the tooth was present so that the bone does not "shrink". The bone graft is kept in place with a small piece of material over the top of the tooth socket and with st...
What is the current status of trial NCT06556095?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 44 participants. The study started on 2024-09-16. Estimated completion is 2026-01-08.
What interventions are being tested in trial NCT06556095?
The interventions under investigation include: Dexamethasone 4mg/ml solution (DRUG).
Who is sponsoring clinical trial NCT06556095?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06556095's enrollment target sits among peer trials
44 589th of 2000 higher than 1,401 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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