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NCT06547112 · ClinicalTrials.gov registry record · Phase 1

A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization

A Phase 1 study, sponsored by Washington University School of Medicine.

Completed
Registry status
Phase 1
Development phase
20
Enrollment target

NCT06547112 is a Phase 1 study that has completed, run by Washington University School of Medicine. The registered enrollment target is 20 participants.

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The verdict

NCT06547112, a Phase 1 study, has completed, sponsored by Washington University School of Medicine.

COMPLETED
Registry status
Phase 1
Development phase
20 participants
Enrollment target

Study Summary

This study includes extended CD34+ profiling on the apheresis product of multiple myeloma patients undergoing standard-of-care quad-induction followed by motixafortide + G-CSF mobilization, and in addition, assesses the pharmacodynamics (PD) of motixafortide following "standard" (\~12 hours) vs "early" (\~16 hours) dosing. The investigators hypothesize that quad-induction may alter the stem cell subsets within the mobilized graft. The investigators further hypothesize that standard and early dosing strategies will result in comparable mobilization and stem cell collection rates.

Interventions

  • DRUG G-CSF
  • DRUG Motixafortide

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-10-31
Est. Completion 2025-08-19
Phase Phase 1

What the Registry Record Tells You About NCT06547112

The ClinicalTrials.gov registry entry for NCT06547112 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 2 interventions - of which G-CSF is the first listed.

NCT06547112 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06547112 about?

NCT06547112 is a clinical study titled "A Pharmacodynamic Study of the Apheresis Product of Multiple Myeloma Patients Undergoing Quad-induction Followed by Motixafortide + G-CSF Mobilization". This study includes extended CD34+ profiling on the apheresis product of multiple myeloma patients undergoing standard-of-care quad-induction followed by motixafortide + G-CSF mobilization, and in addition, assesses the pharmacodynamics (PD) of motixafortide following "standard" (\~12 hours) vs "ear...

What is the current status of trial NCT06547112?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-10-31. Estimated completion is 2025-08-19.

What interventions are being tested in trial NCT06547112?

The interventions under investigation include: G-CSF (DRUG), Motixafortide (DRUG).

Who is sponsoring clinical trial NCT06547112?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.