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NCT06528392 · ClinicalTrials.gov registry record · Phase 2
Efgartigimod for Stiff Person Syndrome (ESPS)
A Phase 2 study, sponsored by University of South Florida.
- Not yet
- Registry status
- Phase 2
- Development phase
- 10
- Enrollment target
NCT06528392 is a Phase 2 study that has not yet begun recruiting, run by University of South Florida. The registered enrollment target is 10 participants.
The verdict
NCT06528392, a Phase 2 study, has not yet begun recruiting, sponsored by University of South Florida.
- NOT YET RECRUITING
- Registry status
- Phase 2
- Development phase
- 10 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to examine the proportion of patients with stiff person syndrome with no worsening in stiffness and/or spasms while on efgartigimod-hyaluronidase (EFD) when compared to their current treatment. The main questions it aims to answer are: * proportion of patients with stiff person syndrome with no worsening in DSI and HSS scores * whether there are changes in laboratory values, vital signs, electrocardiogram, or depression, and suicide risk during the trial, as well as the incidence of any adverse events. Participants will come to the clinic up to 18 times and have up to 5 phone call visits during the course of the trial. During these visits a variety of measures will be collected, including blood samples, neurological and physical exams, patient reported outcomes on stiffness, spasms, depression, and suicide risk.
Interventions
- BIOLOGICAL Efgartigimod
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-04-01 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06528392
The ClinicalTrials.gov registry entry for NCT06528392 describes a study currently listed as not yet recruiting, categorized as Phase 2. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of South Florida, which has 252 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Efgartigimod is the first listed.
NCT06528392 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06528392 about?
NCT06528392 is a clinical study titled "Efgartigimod for Stiff Person Syndrome (ESPS)". The goal of this clinical trial is to examine the proportion of patients with stiff person syndrome with no worsening in stiffness and/or spasms while on efgartigimod-hyaluronidase (EFD) when compared to their current treatment. The main questions it aims to answer are: * proportion of patients wit...
What is the current status of trial NCT06528392?
This trial is currently not yet recruiting. It is a Phase 2 study. The enrollment target is 10 participants. The study started on 2025-04-01. Estimated completion is 2027-12-31.
What interventions are being tested in trial NCT06528392?
The interventions under investigation include: Efgartigimod (BIOLOGICAL).
Who is sponsoring clinical trial NCT06528392?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
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