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NCT06523803 · ClinicalTrials.gov registry record · Phase 1
A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers
A Phase 1 study, sponsored by Zymeworks BC.
- Terminated
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
NCT06523803: Clinical Trial Phase 1 study, sponsored by Zymeworks BC.
NCT06523803 is a Phase 1 study that was terminated before completion, run by Zymeworks BC. The registered enrollment target is 32 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06523803, a Phase 1 study, was terminated before completion, sponsored by Zymeworks BC.
- TERMINATED
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
Study Summary
This study is being done to find out if ZW171 is safe and can treat participants with advanced (locally advanced \[inoperable\] and/or metastatic) mesothelin-expressing cancers.
Primary Outcome
Number of participants who experienced a DLT. DLTs include specifically defined adverse events (AEs) considered to be related to ZW171
Interventions
- DRUG ZW171
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2024-09-30 |
| Est. Completion | 2025-10-01 |
| Phase | Phase 1 |
Why NCT06523803 stopped before completion
NCT06523803 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (47% lower).
The record links to 0 conditions, and to 1 intervention - of which ZW171 is the first listed.
NCT06523803 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06523803 about?
NCT06523803 is a clinical study titled "A Study of ZW171 in Participants With Advanced or Metastatic Mesothelin-expressing Cancers". This study is being done to find out if ZW171 is safe and can treat participants with advanced (locally advanced \[inoperable\] and/or metastatic) mesothelin-expressing cancers.
What is the current status of trial NCT06523803?
This trial is currently terminated. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2024-09-30. Estimated completion is 2025-10-01.
What interventions are being tested in trial NCT06523803?
The interventions under investigation include: ZW171 (DRUG).
Who is sponsoring clinical trial NCT06523803?
This trial is sponsored by Zymeworks BC, which has 4 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06523803's enrollment target sits among peer trials
32 1296th of 2000 higher than 679 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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