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NCT06515782 · ClinicalTrials.gov registry record · NA

Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)

A NA study of Multiple Sclerosis, sponsored by University of Southern California.

Recruiting
Registry status
NA
Development phase
50
Enrollment target
1
Study location

NCT06515782 is a NA study of Multiple Sclerosis that is actively recruiting participants, run by University of Southern California. The registered enrollment target is 50 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06515782, a NA study of Multiple Sclerosis, is actively recruiting participants, sponsored by University of Southern California.

RECRUITING
Registry status
NA
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

In the proposed study, investigators will assess the safety and feasibility of cycles of a fasting mimicking diet (FMD) and its effect on Multiple Sclerosis Quality of Life (MSQOL) in relapsing MS (RMS) patients treated with standard disease modifying therapies (FMDMS). To test the primary hypothesis, investigators will compare the composite quality of life score in terms of improvement in disability, fatigue, and cognitive function with the fasting protocol, as compared to a Mediterranean diet (control) group alone. Further, investigators hypothesize that the effects will remain for at least 6-months after the last FMD cycle. The Mediterranean diet (MD) has been chosen as the control diet to minimize baseline dietary differences among patients. It has been trialed for feasibility in Multiple Sclerosis patients and used in a previous human FMD trial for MS patients where a FMD followed by MD was shown to have positive effects on people with MS.

Conditions Studied

Interventions

  • OTHER Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis.

Study Locations (1)

California

  • Keck School of Medicine of the University of Southern California - Los Angeles

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2023-10-20
Est. Completion 2025-10-20
Phase NA

Sponsor

University of Southern California

617 total trials

What the Registry Record Tells You About NCT06515782

The ClinicalTrials.gov registry entry for NCT06515782 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (91% lower). The listed sponsor is University of Southern California, which has 617 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis. is the first listed.

NCT06515782 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT06515782 about?

NCT06515782 is a clinical study titled "Effect of a Fasting Mimicking Diet on Patients With Multiple Sclerosis (FMDMS)". In the proposed study, investigators will assess the safety and feasibility of cycles of a fasting mimicking diet (FMD) and its effect on Multiple Sclerosis Quality of Life (MSQOL) in relapsing MS (RMS) patients treated with standard disease modifying therapies (FMDMS). To test the primary hypothes...

What is the current status of trial NCT06515782?

This trial is currently recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2023-10-20. Estimated completion is 2025-10-20.

What conditions does trial NCT06515782 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT06515782?

The interventions under investigation include: Med Diet. Investigators would like to see what differences a Mediterranean Diet makes to the status of patients with Multiple Sclerosis. (OTHER).

Who is sponsoring clinical trial NCT06515782?

This trial is sponsored by University of Southern California, which has 617 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06515782 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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