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NCT06511544 · ClinicalTrials.gov registry record · NA
rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression
A NA study of Depression, Treatment Resistant, sponsored by Indiana University.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06511544 is a NA study of Depression, Treatment Resistant that is actively recruiting participants, run by Indiana University. The registered enrollment target is 20 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06511544, a NA study of Depression, Treatment Resistant, is actively recruiting participants, sponsored by Indiana University.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in adults with major depression that has not responded to at least one medication trial. The main question it aims to answer are: Does TMS to the VMPFC change brain activity on functional magnetic resonance imaging (fMRI) during a negative self-referential processing task in adults with depression? Does TMS to the VMPFC affect rumination in adults with depression? Researchers will compare brain scans and rumination scores before, during, and immediately after TMS. Participants will: Undergo three functional MRI scans Undergo a course of 20 TMS treatments Respond to clinical questionnaires and complete a computer behavioral task
Conditions Studied
Interventions
- DEVICE Transcranial magnetic stimulation
Study Locations (1)
Indiana
- Goodman Hall Neuroscience Center - Indianapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-01-02 |
| Est. Completion | 2026-06-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06511544
The ClinicalTrials.gov registry entry for NCT06511544 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indiana University, which has 890 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Depression, Treatment Resistant appearing as the primary indexed condition, and to 1 intervention - of which Transcranial magnetic stimulation is the first listed.
NCT06511544 reports 1 study location spanning 1 distinct geographic area - top geographies include Indiana.
Frequently Asked Questions
What is clinical trial NCT06511544 about?
NCT06511544 is a clinical study titled "rTMS to Target Neural Connectivity and Rumination in Treatment-Resistant Depression". The goal of this clinical trial is to learn if Transcranial Magnetic Stimulation (TMS) to part of the brain called the ventromedial prefrontal cortex (VMPFC) can treat a symptom called rumination in adults with major depression that has not responded to at least one medication trial. The main questi...
What is the current status of trial NCT06511544?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2024-01-02. Estimated completion is 2026-06-30.
What conditions does trial NCT06511544 study?
This clinical trial studies the following conditions: Depression, Treatment Resistant.
What interventions are being tested in trial NCT06511544?
The interventions under investigation include: Transcranial magnetic stimulation (DEVICE).
Who is sponsoring clinical trial NCT06511544?
This trial is sponsored by Indiana University, which has 890 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06511544 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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