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NCT06504368 · ClinicalTrials.gov registry record · Phase 1
Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors
A Phase 1 study of Solid Tumors, Adult, sponsored by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 32
- Enrollment target
- 2
- Study locations
NCT06504368: Recruiting Phase 1 study of Solid Tumors, Adult, sponsored by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company.
NCT06504368 is a Phase 1 study of Solid Tumors, Adult that is actively recruiting participants, run by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company. The registered enrollment target is 32 participants, below the 254-participant average among 5 other Solid Tumors, Adult trials with a reported enrollment target (87% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06504368, a Phase 1 study of Solid Tumors, Adult, is actively recruiting participants, sponsored by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 32 participants
- Enrollment target
- 2
- Study locations
Study Summary
The study will evaluate the safety, tolerability, and pharmacokinetics of intravenous DCR-PDL1 in adults with solid tumors. Participants will be enrolled in one of 4 ascending-dose cohorts. Each treatment cycle will consist of multiple intravenous (IV) doses. Dose escalation decisions will be based on data collected during the dose-limiting toxicity (DLT) period.
Conditions Studied
Interventions
- DRUG DCR-PDL1
Study Locations (2)
Texas
- NEXT Oncology - Irving
- Next Oncology - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 32 participants |
| Start Date | 2024-05-29 |
| Est. Completion | 2027-12-31 |
| Phase | Phase 1 |
What NCT06504368 shows while recruiting
NCT06504368 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 32 participants, a relatively small participant target, below the 254-participant average among 5 other Solid Tumors, Adult trials with a reported enrollment target (87% lower).
The record links to 1 condition, with Solid Tumors, Adult appearing as the primary indexed condition, and to 1 intervention - of which DCR-PDL1 is the first listed.
NCT06504368 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT06504368 about?
NCT06504368 is a clinical study titled "Safety, Tolerability, and Pharmacokinetics of DCR-PDL1 in Adults With Solid Tumors". The study will evaluate the safety, tolerability, and pharmacokinetics of intravenous DCR-PDL1 in adults with solid tumors. Participants will be enrolled in one of 4 ascending-dose cohorts. Each treatment cycle will consist of multiple intravenous (IV) doses. Dose escalation decisions will be based ...
What is the current status of trial NCT06504368?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 32 participants. The study started on 2024-05-29. Estimated completion is 2027-12-31.
What conditions does trial NCT06504368 study?
This clinical trial studies the following conditions: Solid Tumors, Adult.
What interventions are being tested in trial NCT06504368?
The interventions under investigation include: DCR-PDL1 (DRUG).
Who is sponsoring clinical trial NCT06504368?
This trial is sponsored by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company, which has 13 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06504368 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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