Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06499181 · ClinicalTrials.gov registry record · Early Phase 1
Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.
A Early Phase 1 study, sponsored by United States Naval Medical Center, San Diego.
- Completed
- Registry status
- Early Phase 1
- Development phase
- 86
- Enrollment target
NCT06499181: Completed Early Phase 1 study, sponsored by United States Naval Medical Center, San Diego.
NCT06499181 is a Early Phase 1 study that has completed, run by United States Naval Medical Center, San Diego. The registered enrollment target is 86 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06499181, a Early Phase 1 study, has completed, sponsored by United States Naval Medical Center, San Diego.
- COMPLETED
- Registry status
- Early Phase 1
- Development phase
- 86 participants
- Enrollment target
Study Summary
A prospective, randomized clinical trial to determine if using liposomal bupivicaine in maxillary orthognathic procedures can reduce the post-operative use of opioids as well as improving the patient's quality of life, versus traditional bupivicaine alone.
Primary Outcome
The primary objective is to examine differences in post-operative opioid consumption between the two groups
Interventions
- DRUG Bupivacain
- DRUG Liposomal bupivacaine
- DRUG Epinephrin
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 86 participants |
| Start Date | 2018-02-28 |
| Est. Completion | 2020-01-01 |
| Phase | Early Phase 1 |
What the finished NCT06499181 record still lists
NCT06499181 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (62% higher).
The record links to 0 conditions, and to 3 interventions - of which Bupivacain is the first listed.
NCT06499181 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06499181 about?
NCT06499181 is a clinical study titled "Multimodal Orthognathic Study Comparing Use of Exparel With Standard of Care.". A prospective, randomized clinical trial to determine if using liposomal bupivicaine in maxillary orthognathic procedures can reduce the post-operative use of opioids as well as improving the patient's quality of life, versus traditional bupivicaine alone.
What is the current status of trial NCT06499181?
This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 86 participants. The study started on 2018-02-28. Estimated completion is 2020-01-01.
What interventions are being tested in trial NCT06499181?
The interventions under investigation include: Bupivacain (DRUG), Liposomal bupivacaine (DRUG), Epinephrin (DRUG).
Who is sponsoring clinical trial NCT06499181?
This trial is sponsored by United States Naval Medical Center, San Diego, which has 41 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06499181's enrollment target sits among peer trials
86 256th of 2000 higher than 1,741 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01639508 · 86 participants · Phase 2
Cabozantinib in Patients With RET Fusion-Positive Advanced Non-Small Cell Lung Cancer and Those With Other Genotypes: ROS1 or NTRK Fusions or Increased MET or AXL Activity
- NCT03519269 · 86 participants · NA
Navio Robotic Versus Conventional Total Knee Arthroplasty
- NCT04132999 · 86 participants · NA
PAP for Children With DS and OSAS
- NCT04545957 · 86 participants · NA
Jump: MR Simulation For Radiation Therapy Master Protocol
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI