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NCT06477146 · ClinicalTrials.gov registry record · Phase 2
Milk Thistle Clinical Trial in Pediatric NAFLD
A Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD), sponsored by University Hospitals Cleveland Medical Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06477146: Recruiting Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD), sponsored by University Hospitals Cleveland Medical Center.
NCT06477146 is a Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD) that is actively recruiting participants, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 20 participants, below the 89-participant average among 9 other Non-Alcoholic Fatty Liver Disease (NAFLD) trials with a reported enrollment target (78% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06477146, a Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD), is actively recruiting participants, sponsored by University Hospitals Cleveland Medical Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is to investigate alternative medical therapy with an herbal supplement called Milk Thistle (MT) which may improve fatty liver disease and would be easier to follow than diet and exercise.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Milk thistle (MT)
- BEHAVIORAL Lifestyle Modification
- DEVICE Fibroscan
Study Locations (1)
Ohio
- University Hospitals Cleveland Medical Center - Cleveland
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-12-19 |
| Est. Completion | 2029-01-31 |
| Phase | Phase 2 |
What NCT06477146 shows while recruiting
NCT06477146 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 89-participant average among 9 other Non-Alcoholic Fatty Liver Disease (NAFLD) trials with a reported enrollment target (78% lower).
The record links to 1 condition, with Non-Alcoholic Fatty Liver Disease (NAFLD) appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.
NCT06477146 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT06477146 about?
NCT06477146 is a clinical study titled "Milk Thistle Clinical Trial in Pediatric NAFLD". Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is t...
What is the current status of trial NCT06477146?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-12-19. Estimated completion is 2029-01-31.
What conditions does trial NCT06477146 study?
This clinical trial studies the following conditions: Non-Alcoholic Fatty Liver Disease (NAFLD).
What interventions are being tested in trial NCT06477146?
The interventions under investigation include: Placebo (DRUG), Milk thistle (MT) (DRUG), Lifestyle Modification (BEHAVIORAL), Fibroscan (DEVICE).
Who is sponsoring clinical trial NCT06477146?
This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06477146 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Non-Alcoholic Fatty Liver Disease (NAFLD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06477146's enrollment target sits among peer trials
20 8th of 9 higher than 1 of 9 other Non-Alcoholic Fatty Liver Disease (NAFLD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Non-Alcoholic Fatty Liver Disease (NAFLD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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