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NCT06477146 · ClinicalTrials.gov registry record · Phase 2

Milk Thistle Clinical Trial in Pediatric NAFLD

A Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD), sponsored by University Hospitals Cleveland Medical Center.

Recruiting
Registry status
Phase 2
Development phase
20
Enrollment target
1
Study location

NCT06477146 is a Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD) that is actively recruiting participants, run by University Hospitals Cleveland Medical Center. The registered enrollment target is 20 participants, below the 70-participant average among 6 other Non-Alcoholic Fatty Liver Disease (NAFLD) trials with a reported enrollment target (71% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06477146, a Phase 2 study of Non-Alcoholic Fatty Liver Disease (NAFLD), is actively recruiting participants, sponsored by University Hospitals Cleveland Medical Center.

RECRUITING
Registry status
Phase 2
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is to investigate alternative medical therapy with an herbal supplement called Milk Thistle (MT) which may improve fatty liver disease and would be easier to follow than diet and exercise.

Conditions Studied

Non-Alcoholic Fatty Liver Disease (NAFLD)

Interventions

  • DRUG Placebo
  • DRUG Milk thistle (MT)
  • BEHAVIORAL Lifestyle Modification
  • DEVICE Fibroscan

Study Locations (1)

Ohio

  • University Hospitals Cleveland Medical Center - Cleveland

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-12-19
Est. Completion 2029-01-31
Phase Phase 2

Sponsor

University Hospitals Cleveland Medical Center

230 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06477146

The ClinicalTrials.gov registry entry for NCT06477146 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 70-participant average among 6 other Non-Alcoholic Fatty Liver Disease (NAFLD) trials with a reported enrollment target (71% lower). The listed sponsor is University Hospitals Cleveland Medical Center, which has 230 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Non-Alcoholic Fatty Liver Disease (NAFLD) appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT06477146 reports 1 study location spanning 1 distinct geographic area - top geographies include Ohio.

Frequently Asked Questions

What is clinical trial NCT06477146 about?

NCT06477146 is a clinical study titled "Milk Thistle Clinical Trial in Pediatric NAFLD". Pediatric Fatty Liver disease is a growing problem in the United States and is expected to be the leading cause of Liver Transplantation in Adults in 20 years. Following lifestyle changes such as diet restrictions and exercise may be difficult to consistently maintain. The purpose of this study is t...

What is the current status of trial NCT06477146?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-12-19. Estimated completion is 2029-01-31.

What conditions does trial NCT06477146 study?

This clinical trial studies the following conditions: Non-Alcoholic Fatty Liver Disease (NAFLD).

What interventions are being tested in trial NCT06477146?

The interventions under investigation include: Placebo (DRUG), Milk thistle (MT) (DRUG), Lifestyle Modification (BEHAVIORAL), Fibroscan (DEVICE).

Who is sponsoring clinical trial NCT06477146?

This trial is sponsored by University Hospitals Cleveland Medical Center, which has 230 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06477146 being conducted?

This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.