Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06467825 · ClinicalTrials.gov registry record · NA
Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent
A NA study of Healthy, sponsored by National Aeronautics and Space Administration (NASA).
- Recruiting
- Registry status
- NA
- Development phase
- 38
- Enrollment target
- 1
- Study location
NCT06467825 is a NA study of Healthy that is actively recruiting participants, run by National Aeronautics and Space Administration (NASA). The registered enrollment target is 38 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.
The verdict
NCT06467825, a NA study of Healthy, is actively recruiting participants, sponsored by National Aeronautics and Space Administration (NASA).
- RECRUITING
- Registry status
- NA
- Development phase
- 38 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of Lunar OI (Orthostatic Intolerance) is to determine if there are differences between males and females in tolerance to and cardiovascular responses during different angles of head-up tilt simulating gravity levels less than or equal to Earth's gravity. Also, this study will determine if a gradient compression garment affects tolerance to tilting and the cardiovascular stress at different tilt angles. Males and females are being identified by biological sex. This will be a two-phased study design. In Phase I we will determine whether there are differences in the development of signs or symptoms of orthostatic intolerance between males and females when tilted head up on a table to different angles to simulate gravity levels that astronauts may experience when landing on or launching from the surface of the Moon. In Phase II, the tilt tests simulating the same gravity levels from Phase I will be repeated, but a custom-made lower-body compression garment will be worn to see if wearing the garment affects the development of orthostatic intolerance. For both study phases, before tilting, a drug will be administered to reduce the amount fluid in the blood (plasma) to levels similar to that experienced by astronauts during spaceflight.
Conditions Studied
Interventions
- DRUG Potassium Supplement
- DRUG Furosemide 20 MG
- DEVICE Compression Garment
Study Locations (1)
Texas
- NASA - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 38 participants |
| Start Date | 2022-08-09 |
| Est. Completion | 2025-09 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06467825
The ClinicalTrials.gov registry entry for NCT06467825 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (94% lower). The listed sponsor is National Aeronautics and Space Administration (NASA), which has 8 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Potassium Supplement is the first listed.
NCT06467825 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.
Frequently Asked Questions
What is clinical trial NCT06467825 about?
NCT06467825 is a clinical study titled "Effect of Sex on Orthostatic Intolerance and Cardiovascular Response During Lunar Descent and Ascent". The purpose of Lunar OI (Orthostatic Intolerance) is to determine if there are differences between males and females in tolerance to and cardiovascular responses during different angles of head-up tilt simulating gravity levels less than or equal to Earth's gravity. Also, this study will determine i...
What is the current status of trial NCT06467825?
This trial is currently recruiting. It is a NA study. The enrollment target is 38 participants. The study started on 2022-08-09. Estimated completion is 2025-09.
What conditions does trial NCT06467825 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT06467825?
The interventions under investigation include: Potassium Supplement (DRUG), Furosemide 20 MG (DRUG), Compression Garment (DEVICE).
Who is sponsoring clinical trial NCT06467825?
This trial is sponsored by National Aeronautics and Space Administration (NASA), which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06467825 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Neuromodulation-assisted Ego-disengagement: The NEURO-EGO Study Stage 1
RECRUITING · NA
-
Oxalate and Citrate in Humans - Response to Citrate
RECRUITING · NA
-
CArdioMEtabolic Function and Reserve Capacity in Healthy Adults: The CAMERA Study
RECRUITING · NA
-
Examining Bronchial Hyperresponsiveness in Primary Ciliary Dyskinesia
RECRUITING · NA
-
Medical Illustration Design Characteristic Evaluation
RECRUITING · NA
-
Sodium vs Potassium Education to Improve Vascular Health
RECRUITING · NA
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.