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NCT06454058 · ClinicalTrials.gov registry record
Association Between Euploid Embryo Grade and Maternal Age
A clinical trial, sponsored by Inception Fertility Research Institute.
- Terminated
- Registry status
- 502
- Enrollment target
NCT06454058: Clinical Trial study, sponsored by Inception Fertility Research Institute.
NCT06454058 is a clinical trial that was terminated before completion, run by Inception Fertility Research Institute. The registered enrollment target is 502 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06454058 was terminated before completion, sponsored by Inception Fertility Research Institute.
- TERMINATED
- Registry status
- 502 participants
- Enrollment target
Study Summary
Background: Advanced maternal age (AMA) is associated with a reduction in live birth rate (LBR) after ART cycles. The main reason for this reduction is the lower number of oocytes aspirated, the number of developing embryos and the low number of euploid embryos available for transfer. The impact of age on success rates after the transfer of an euploid embryo has been a matter of discussion, with a recent meta-analysis showing a reduction in LBR after the transfer of an euploid blastocyst to women of AMA (1). There could be many reasons for this reduced LBR but they can be categorized into two broad categories - the uterus (including the mother's health) and the embryo (including the oocyte and the sperm). It is possible that factors associated with reduced embryo quality would manifest in a lower embryo grade.
Primary Outcome
Embryo grade for PGT-A confirmed euploid embryos
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 502 participants |
| Start Date | 2024-06-07 |
| Est. Completion | 2025-03-26 |
Why NCT06454058 stopped before completion
NCT06454058 is an observational study that tracks outcomes without assigning an intervention. The registered 502 participants enrollment target is mid-sized for trials with a published cap.
The record links to 0 conditions, and to 0 interventions.
NCT06454058 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06454058 about?
NCT06454058 is a clinical study titled "Association Between Euploid Embryo Grade and Maternal Age". Background: Advanced maternal age (AMA) is associated with a reduction in live birth rate (LBR) after ART cycles. The main reason for this reduction is the lower number of oocytes aspirated, the number of developing embryos and the low number of euploid embryos available for transfer. The impact of ...
What is the current status of trial NCT06454058?
This trial is currently terminated. The enrollment target is 502 participants. The study started on 2024-06-07. Estimated completion is 2025-03-26.
Who is sponsoring clinical trial NCT06454058?
This trial is sponsored by Inception Fertility Research Institute, which has 9 total clinical trials registered on ClinicalTrials.gov.
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