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NCT06448039 · ClinicalTrials.gov registry record · Phase 1
In-office Repair of Chronic Tympanic Membrane Perforations
A Phase 1 study, sponsored by D. Bradley Welling, MD, PhD.
- Active
- Registry status
- Phase 1
- Development phase
- 20
- Enrollment target
NCT06448039 is a Phase 1 study that is active but no longer recruiting, run by D. Bradley Welling, MD, PhD. The registered enrollment target is 20 participants.
The verdict
NCT06448039, a Phase 1 study, is active but no longer recruiting, sponsored by D. Bradley Welling, MD, PhD.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 1
- Development phase
- 20 participants
- Enrollment target
Study Summary
The goal of this clinical trial is to compare the application of fibroblast growth factor 2 (FGF2) with normal saline for the healing of chronic tympanic membrane (TM) perforations. This is an extension of a prior study. The main question it aims to answer is: Will modifications to our prior surgical trial provide higher success rates in obtaining complete closure of chronic tympanic membrane perforations? Twenty participants will be randomized in a controlled study to FGF2 or saline in a 3:1 ratio and the total tympanic membrane closure compared.
Interventions
- DRUG Fibroblast Growth Factor 2
- DRUG Saline control
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-06-15 |
| Est. Completion | 2026-12-30 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06448039
The ClinicalTrials.gov registry entry for NCT06448039 describes a study currently listed as active not recruiting, categorized as Phase 1. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is D. Bradley Welling, MD, PhD, which has 3 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 2 interventions - of which Fibroblast Growth Factor 2 is the first listed.
NCT06448039 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06448039 about?
NCT06448039 is a clinical study titled "In-office Repair of Chronic Tympanic Membrane Perforations". The goal of this clinical trial is to compare the application of fibroblast growth factor 2 (FGF2) with normal saline for the healing of chronic tympanic membrane (TM) perforations. This is an extension of a prior study. The main question it aims to answer is: Will modifications to our prior surgic...
What is the current status of trial NCT06448039?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 20 participants. The study started on 2024-06-15. Estimated completion is 2026-12-30.
What interventions are being tested in trial NCT06448039?
The interventions under investigation include: Fibroblast Growth Factor 2 (DRUG), Saline control (DRUG).
Who is sponsoring clinical trial NCT06448039?
This trial is sponsored by D. Bradley Welling, MD, PhD, which has 3 total clinical trials registered on ClinicalTrials.gov.
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