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NCT06446739 · ClinicalTrials.gov registry record · NA
LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)
A NA study, sponsored by University of Alberta.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
NCT06446739 is a NA study that is actively recruiting participants, run by University of Alberta. The registered enrollment target is 100 participants.
The verdict
NCT06446739, a NA study, is actively recruiting participants, sponsored by University of Alberta.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
Study Summary
An estimated 10-15% of critically ill patients with acute kidney failure in the intensive care unit receive acute dialysis therapy. The majority of these patients initially receive a continuous form of dialysis therapy call continuous renal replacement therapy (CRRT). Prior studies have suggested that higher CRRT dose-intensity improved health outcomes for these patients; however, this was not found in high-quality clinical trials. These more recent trials suggested a lower range of dose-intensity compared with the higher range as the new standard of care. This was incorporated into guidelines. To date, no clinical trials have evaluated this lower range and specifically, it is plausible that an even lower dose-intensity of CRRT may be well tolerated, safe, associated with similar outcomes and be more cost-effective. This is the objective of the WISDOM trial, to compare the guideline standard with lower dose-intensity among patients who are started on CRRT in the intensive care unit.
Interventions
- DEVICE Continuous Renal Replacement Therapy (CRRT)
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-11-14 |
| Est. Completion | 2027-06 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06446739
The ClinicalTrials.gov registry entry for NCT06446739 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Alberta, which has 19 total studies on file at ClinicalTrials.gov.
The record links to 0 conditions, and to 1 intervention - of which Continuous Renal Replacement Therapy (CRRT) is the first listed.
NCT06446739 reports 0 study locations.
Frequently Asked Questions
What is clinical trial NCT06446739 about?
NCT06446739 is a clinical study titled "LoW Dose-Intensity vs. Standard Dose-Intensity COntinuous Renal ReplaceMent Therapy in Critically Ill Patients (WISDOM)". An estimated 10-15% of critically ill patients with acute kidney failure in the intensive care unit receive acute dialysis therapy. The majority of these patients initially receive a continuous form of dialysis therapy call continuous renal replacement therapy (CRRT). Prior studies have suggested th...
What is the current status of trial NCT06446739?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2024-11-14. Estimated completion is 2027-06.
What interventions are being tested in trial NCT06446739?
The interventions under investigation include: Continuous Renal Replacement Therapy (CRRT) (DEVICE).
Who is sponsoring clinical trial NCT06446739?
This trial is sponsored by University of Alberta, which has 19 total clinical trials registered on ClinicalTrials.gov.
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