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NCT06442930 · ClinicalTrials.gov registry record
EXtubation Related Complications - the EXTUBE Study (EXTUBE)
A clinical trial of Extubation, sponsored by University Health Network, Toronto.
- Recruiting
- Registry status
- 3,000
- Enrollment target
- 20
- Study locations
NCT06442930: Recruiting study of Extubation, sponsored by University Health Network, Toronto.
NCT06442930 is a study of Extubation that is actively recruiting participants, run by University Health Network, Toronto. The registered enrollment target is 3,000 participants. The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06442930, a study of Extubation, is actively recruiting participants, sponsored by University Health Network, Toronto.
- RECRUITING
- Registry status
- 3,000 participants
- Enrollment target
- 20
- Study locations
Study Summary
EXTUBE is an international, multicentre, prospective cohort study evaluating the incidence, risk factors, and outcomes of extubation-related complications and describing clinical practices related to extubation after general anesthesia or after critical illness in the operating room (OR), out of OR anesthesia location or intensive care unit (ICU).
Primary Outcome
The primary outcome will be the occurrence of at least one of the following (composite outcome) occurring within 60 minutes after the end of extubation: i) Severe hypoxemia (oxygen saturation as measured by pulse oximetry falls below SpO2 \< 80% for \> 5 minutes) ii) Cardiac arrest iii) Need for airway management (reintubation, insertion of a supraglottic airway, bag-mask ventilation).
Conditions Studied
Study Locations (20)
Ontario
- Sunnybrook Hospital - North York
- Niagara Health - Marotta Family Hospital - Saint Catharines
- St. Michael's Hospital - Toronto
- Mount Sinai Hospital - Toronto
- University Health Network - Toronto General Hospital - Toronto
- University Health Network - Toronto Western Hospital - Toronto
Victoria
- The Northern Hospital - Melbourne
- Austin Hospital - Melbourne
- Eastern Health - Box Hill Hospital - Melbourne
- Eastern Health - Maroondah Hospital - Melbourne
- Eastern Health - Angliss Hospital - Melbourne
Arizona
- Banner University Medical Centre - Tucson
Arkansas
- University of Arkansas for Medical Sciences - Little Rock
Florida
- University of Florida - Gainesville
Oregon
- Oregon Health & Science University - Portland
Texas
- The University of Texas Health Science Center - Houston
New South Wales
- Royal North Shore Hospital - Sydney
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3,000 participants |
| Start Date | 2025-04-14 |
| Est. Completion | 2026-12 |
What NCT06442930 shows while recruiting
NCT06442930 is an observational study that tracks outcomes without assigning an intervention. Its 3,000 participants enrollment target places it among the larger protocols in the corpus.
The record links to 1 condition, with Extubation appearing as the primary indexed condition, and to 0 interventions.
NCT06442930 names 20 study sites across 11 states, led by Ontario, Victoria, Arizona.
Frequently Asked Questions
What is clinical trial NCT06442930 about?
NCT06442930 is a clinical study titled "EXtubation Related Complications - the EXTUBE Study (EXTUBE)". EXTUBE is an international, multicentre, prospective cohort study evaluating the incidence, risk factors, and outcomes of extubation-related complications and describing clinical practices related to extubation after general anesthesia or after critical illness in the operating room (OR), out of OR ...
What is the current status of trial NCT06442930?
This trial is currently recruiting. The enrollment target is 3,000 participants. The study started on 2025-04-14. Estimated completion is 2026-12.
What conditions does trial NCT06442930 study?
This clinical trial studies the following conditions: Extubation.
Who is sponsoring clinical trial NCT06442930?
This trial is sponsored by University Health Network, Toronto, which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06442930 being conducted?
This trial has 20 study locations across Arizona, Arkansas, Florida, Oregon, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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