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NCT06442475 · ClinicalTrials.gov registry record · Phase 2
Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma
A Phase 2 study of Grade 3a Follicular Lymphoma and Grade 1 Follicular Lymphoma, sponsored by University of Washington.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06442475: Recruiting Phase 2 study of Grade 3a Follicular Lymphoma and Grade 1 Follicular Lymphoma, sponsored by University of Washington.
NCT06442475 is a Phase 2 study of Grade 3a Follicular Lymphoma and Grade 1 Follicular Lymphoma that is actively recruiting participants, run by University of Washington. The registered enrollment target is 20 participants, below the 41-participant average among 10 other Grade 3a Follicular Lymphoma trials with a reported enrollment target (51% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06442475, a Phase 2 study of Grade 3a Follicular Lymphoma and Grade 1 Follicular Lymphoma, is actively recruiting participants, sponsored by University of Washington.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
This phase II trial tests the safety, side effects and effectiveness of mosunetuzumab in treating patients with slow growing (indolent) B-cell lymphoma. Mosunetuzumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread.
Primary Outcome
OR will be defined as complete response and partial response at the end of therapy based on the latest version of Lugano criteria. Response rates will be calculated using simple binomial proportions and the corresponding 95% confidence interval will be derived.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Computed Tomography
- PROCEDURE Magnetic Resonance Imaging
- PROCEDURE Positron Emission Tomography
- BIOLOGICAL Mosunetuzumab
Study Locations (1)
Washington
- Fred Hutch/University of Washington Cancer Consortium - Seattle
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-08-29 |
| Est. Completion | 2027-02-12 |
| Phase | Phase 2 |
What NCT06442475 shows while recruiting
NCT06442475 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 41-participant average among 10 other Grade 3a Follicular Lymphoma trials with a reported enrollment target (51% lower).
The record links to 9 conditions, with Grade 3a Follicular Lymphoma appearing as the primary indexed condition, and to 5 interventions - of which Biospecimen Collection is the first listed.
NCT06442475 reports a single indexed study location in Washington.
Frequently Asked Questions
What is clinical trial NCT06442475 about?
NCT06442475 is a clinical study titled "Low Dose Mosunetuzumab for the Treatment of Patients With Indolent B-Cell Lymphoma". This phase II trial tests the safety, side effects and effectiveness of mosunetuzumab in treating patients with slow growing (indolent) B-cell lymphoma. Mosunetuzumab is a monoclonal antibody that may interfere with the ability of tumor cells to grow and spread.
What is the current status of trial NCT06442475?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-08-29. Estimated completion is 2027-02-12.
What conditions does trial NCT06442475 study?
This clinical trial studies the following conditions: Grade 3a Follicular Lymphoma, Grade 1 Follicular Lymphoma, Grade 2 Follicular Lymphoma, Ann Arbor Stage II Follicular Lymphoma, Ann Arbor Stage III Follicular Lymphoma.
What interventions are being tested in trial NCT06442475?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Computed Tomography (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Positron Emission Tomography (PROCEDURE), Mosunetuzumab (BIOLOGICAL).
Who is sponsoring clinical trial NCT06442475?
This trial is sponsored by University of Washington, which has 1,048 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06442475 being conducted?
This trial has 1 study location across Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Grade 3a Follicular Lymphoma
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06442475's enrollment target sits among peer trials
20 11th of 10 the lowest of 10 other Grade 3a Follicular Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Grade 3a Follicular Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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