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NCT06436612 · ClinicalTrials.gov registry record · Phase 2
Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)
A Phase 2 study of Abdominopelvic Sarcomas, sponsored by Jonsson Comprehensive Cancer Center.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT06436612: Recruiting Phase 2 study of Abdominopelvic Sarcomas, sponsored by Jonsson Comprehensive Cancer Center.
NCT06436612 is a Phase 2 study of Abdominopelvic Sarcomas that is actively recruiting participants, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 20 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06436612, a Phase 2 study of Abdominopelvic Sarcomas, is actively recruiting participants, sponsored by Jonsson Comprehensive Cancer Center.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Recent advances in radiation treatment have allowed for higher doses per treatment to be delivered safely. This study plans to use an MRI-guided linear accelerator to deliver the radiation treatment to ensure that the radiation dose is administered to the cancerous tumor, not the vital body organs. Potential participants with a sarcoma diagnosis will be referred to Radiation Oncology during this study. If the participant is interested in participating in this study, s/he receives radiation treatment daily for 5 consecutive days except for weekends and holidays. Within 12 weeks of completing the radiation therapy, the participant will have the primary tumor surgically removed. The radiation oncology team will follow the patients for 5 years after completing radiation therapy.
Primary Outcome
Evaluate the 2 year rate of grade ≥2 radiation morbidity, according to Common Terminology Criteria for Adverse Events (CTCAE), Version 5.0.
Conditions Studied
Interventions
- RADIATION Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy
Study Locations (1)
California
- UCLA / Jonsson Comprehensive Cancer Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-05-30 |
| Est. Completion | 2028-05-26 |
| Phase | Phase 2 |
What NCT06436612 shows while recruiting
NCT06436612 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Abdominopelvic Sarcomas appearing as the primary indexed condition, and to 1 intervention - of which Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy is the first listed.
NCT06436612 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06436612 about?
NCT06436612 is a clinical study titled "Study of Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy for Abdominopelvic Sarcomas (MARS Trial)". Recent advances in radiation treatment have allowed for higher doses per treatment to be delivered safely. This study plans to use an MRI-guided linear accelerator to deliver the radiation treatment to ensure that the radiation dose is administered to the cancerous tumor, not the vital body organs. ...
What is the current status of trial NCT06436612?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2024-05-30. Estimated completion is 2028-05-26.
What conditions does trial NCT06436612 study?
This clinical trial studies the following conditions: Abdominopelvic Sarcomas.
What interventions are being tested in trial NCT06436612?
The interventions under investigation include: Magnetic Resonance Image and Computed Tomography-Guided Stereotactic Body Radiation Therapy (RADIATION).
Who is sponsoring clinical trial NCT06436612?
This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06436612 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06436612's enrollment target sits among peer trials
20 1805th of 2000 higher than 107 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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