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NCT06430086 · ClinicalTrials.gov registry record · NA
Mechanistic Effect of Walnut Consumption on Sleep Quality
A NA study of Poor Sleep Quality, sponsored by Columbia University.
- Recruiting
- Registry status
- NA
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT06430086: Recruiting NA study of Poor Sleep Quality, sponsored by Columbia University.
NCT06430086 is a NA study of Poor Sleep Quality that is actively recruiting participants, run by Columbia University. The registered enrollment target is 24 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06430086, a NA study of Poor Sleep Quality, is actively recruiting participants, sponsored by Columbia University.
- RECRUITING
- Registry status
- NA
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
Poor sleep quality is very common in modern society. Walnuts contain many nutrients that may be helpful for sleep, including melatonin and polyphenols. Some studies show that eating foods high in melatonin and polyphenols improves sleep quality, but walnuts have not been studied specifically. This study proposes to test if eating walnuts improves sleep compared to a food that lacks these sleep-promoting factors. The investigators expect that walnut consumption for 4 days will increase melatonin levels and lead to better sleep quality compared to a high-carbohydrate, high-sugar food. The study will enroll middle-aged and older adults with sleep complaints to participate in this study. Each person will eat the two different foods for 4 days each in random order. The 4-day periods will be separated by at least 2-3 weeks. Sleep quality will be measured by questionnaire and with a wrist monitor every day. The investigators will also do a sleep study using electroencephalography (EEG) on night 3 and take measures of circadian physiology (natural body rhythms) in the laboratory on day 4 (including overnight) by measuring body temperature and blood and urine melatonin. The study findings may provide new options to improve sleep health from increased walnut consumption.
Primary Outcome
Serum melatonin will be measured via last testing of blood samples collected on day 4, in an inpatient setting. Repeated for each phase.
Conditions Studied
Interventions
- OTHER Walnut consumption
- OTHER HCHS consumption
Study Locations (1)
New York
- Columbia University Irving Medical Center - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2024-06-28 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06430086 shows while recruiting
NCT06430086 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Poor Sleep Quality appearing as the primary indexed condition, and to 2 interventions - of which Walnut consumption is the first listed.
NCT06430086 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT06430086 about?
NCT06430086 is a clinical study titled "Mechanistic Effect of Walnut Consumption on Sleep Quality". Poor sleep quality is very common in modern society. Walnuts contain many nutrients that may be helpful for sleep, including melatonin and polyphenols. Some studies show that eating foods high in melatonin and polyphenols improves sleep quality, but walnuts have not been studied specifically. This s...
What is the current status of trial NCT06430086?
This trial is currently recruiting. It is a NA study. The enrollment target is 24 participants. The study started on 2024-06-28. Estimated completion is 2026-12-31.
What conditions does trial NCT06430086 study?
This clinical trial studies the following conditions: Poor Sleep Quality.
What interventions are being tested in trial NCT06430086?
The interventions under investigation include: Walnut consumption (OTHER), HCHS consumption (OTHER).
Who is sponsoring clinical trial NCT06430086?
This trial is sponsored by Columbia University, which has 958 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06430086 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06430086's enrollment target sits among peer trials
24 1736th of 2000 higher than 246 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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