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NCT06414408 · ClinicalTrials.gov registry record · Early Phase 1
Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP
A Early Phase 1 study of Sexually Transmitted Diseases, Bacterial, sponsored by University of California, San Francisco.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 48
- Enrollment target
- 1
- Study location
NCT06414408 is a Early Phase 1 study of Sexually Transmitted Diseases, Bacterial that is actively recruiting participants, run by University of California, San Francisco. The registered enrollment target is 48 participants. The trial reports 1 study location across 1 state.
The verdict
NCT06414408, a Early Phase 1 study of Sexually Transmitted Diseases, Bacterial, is actively recruiting participants, sponsored by University of California, San Francisco.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 48 participants
- Enrollment target
- 1
- Study location
Study Summary
Rates of bacterial sexually transmitted infections (STIs) are rising globally, demanding innovative interventions beyond the scope of current efforts to prevent STIs. The United States Doxycycline Post-exposure Prophylaxis (DoxyPEP) Study has demonstrated the efficacy of doxycycline post-exposure prophylaxis (PEP) among men who have sex with men and transgender women; but puzzlingly, doxycycline PEP was found ineffective in cisgender women in the Kenyan doxycycline Post-Exposure Prophylaxis (dPEP) study, with preliminary data suggesting the low medication adherence may explain the null result. By study end, the investigators will have developed adherence measurement methods for doxycycline in hair, blood, and urine, and will use these techniques to help interpret the Kenyan dPEP study, and to examine the relative performance of these methods within the United States DoxyPEP trial, establishing adherence metrics for current and future rollout studies of doxycycline post-exposure prophylaxis
Conditions Studied
Interventions
- DRUG Doxycycline Pill
Study Locations (1)
California
- University of California, San Francisco/San Francisco General Hospital - San Francisco
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2024-10-18 |
| Est. Completion | 2028-09-01 |
| Phase | Early Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06414408
The ClinicalTrials.gov registry entry for NCT06414408 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Sexually Transmitted Diseases, Bacterial appearing as the primary indexed condition, and to 1 intervention - of which Doxycycline Pill is the first listed.
NCT06414408 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT06414408 about?
NCT06414408 is a clinical study titled "Randomized Directly Observed Therapy Study to Interpret Clinical Trials of Doxy-PEP". Rates of bacterial sexually transmitted infections (STIs) are rising globally, demanding innovative interventions beyond the scope of current efforts to prevent STIs. The United States Doxycycline Post-exposure Prophylaxis (DoxyPEP) Study has demonstrated the efficacy of doxycycline post-exposure pr...
What is the current status of trial NCT06414408?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 48 participants. The study started on 2024-10-18. Estimated completion is 2028-09-01.
What conditions does trial NCT06414408 study?
This clinical trial studies the following conditions: Sexually Transmitted Diseases, Bacterial.
What interventions are being tested in trial NCT06414408?
The interventions under investigation include: Doxycycline Pill (DRUG).
Who is sponsoring clinical trial NCT06414408?
This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06414408 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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