Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06412172 · ClinicalTrials.gov registry record
The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)
A clinical trial of Recurrent Respiratory Papillomatosis and Pulmonary Neoplasm, sponsored by Massachusetts General Hospital.
- Recruiting
- Registry status
- 100
- Enrollment target
- 1
- Study location
NCT06412172 is a study of Recurrent Respiratory Papillomatosis and Pulmonary Neoplasm that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 100 participants, above the 22-participant average among 6 other Recurrent Respiratory Papillomatosis trials with a reported enrollment target (355% higher). The trial reports 1 study location across 1 state.
The verdict
NCT06412172, a study of Recurrent Respiratory Papillomatosis and Pulmonary Neoplasm, is actively recruiting participants, sponsored by Massachusetts General Hospital.
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
Recurrent respiratory papillomatosis (RRP) is an orphan disease that affects approximately 20,000 people in the United States and is caused by infection with human papillomavirus (HPV) types 6 and 11. Since RRP is an orphan disease, it is an understudied disease entity with correspondingly few treatment options. The investigators hypothesize that by understanding the biology of RRP and the failed host immune responses against HPV, novel and rational therapies can be developed. This study will examine the genetic and immunologic alterations found in these rare tumors and distant metastatic involved sites (such as the lung) in patients diagnosed with RRP.
Conditions Studied
Study Locations (1)
Connecticut
- Yale School of Medicine - New Haven
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2024-04-15 |
| Est. Completion | 2030-04-15 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06412172
The ClinicalTrials.gov registry entry for NCT06412172 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 22-participant average among 6 other Recurrent Respiratory Papillomatosis trials with a reported enrollment target (355% higher). The listed sponsor is Massachusetts General Hospital, which has 2,032 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Recurrent Respiratory Papillomatosis appearing as the primary indexed condition, and to 0 interventions.
NCT06412172 reports 1 study location spanning 1 distinct geographic area - top geographies include Connecticut.
Frequently Asked Questions
What is clinical trial NCT06412172 about?
NCT06412172 is a clinical study titled "The Natural History and Biological Study of Pulmonary Recurrent Respiratory Papillomatosis (pRRP)". Recurrent respiratory papillomatosis (RRP) is an orphan disease that affects approximately 20,000 people in the United States and is caused by infection with human papillomavirus (HPV) types 6 and 11. Since RRP is an orphan disease, it is an understudied disease entity with correspondingly few treat...
What is the current status of trial NCT06412172?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2024-04-15. Estimated completion is 2030-04-15.
What conditions does trial NCT06412172 study?
This clinical trial studies the following conditions: Recurrent Respiratory Papillomatosis, Pulmonary Neoplasm.
Who is sponsoring clinical trial NCT06412172?
This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06412172 being conducted?
This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Recurrent Respiratory Papillomatosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Zopa Retreatment and Vector Shedding in Adults With RRP
RECRUITING · Phase 4
-
Merck IIT: RRP Pembro and Lenvatinib
RECRUITING · Early Phase 1
-
Autologous Dendritic Cell Vaccine For Recurrent Respiratory Papillomatosis (RRP) Patients
RECRUITING · Phase 1
-
Adjuvant PRGN-2012 in Adult Patients With Recurrent Respiratory Papillomatosis
ACTIVE NOT RECRUITING · Phase 1
-
Pembrolizumab for HPV-associated Recurrent Respiratory Papilloma Patients
ACTIVE NOT RECRUITING · Phase 2
-
Avelumab for People With Recurrent Respiratory Papillomatosis
COMPLETED · Phase 2
Explore more on PlainTrial
Recurrent Respiratory Papillomatosis
All registered trials for this condition
Pulmonary Neoplasm
All registered trials for this condition
Connecticut
All trials with a study site in Connecticut
Recruiting now
Find trials open to new participants near you
Rankings
Top sponsors, conditions, and phases
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.