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NCT06393452 · ClinicalTrials.gov registry record · Phase 2

Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA

A Phase 2 study of Androgenetic Alopecia, sponsored by Pelage Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
78
Enrollment target
8
Study locations

NCT06393452 is a Phase 2 study of Androgenetic Alopecia that has completed, run by Pelage Pharmaceuticals. The registered enrollment target is 78 participants, below the 160-participant average among 16 other Androgenetic Alopecia trials with a reported enrollment target (51% lower). The trial reports 8 study locations across 6 states.

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The verdict

NCT06393452, a Phase 2 study of Androgenetic Alopecia, has completed, sponsored by Pelage Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
78 participants
Enrollment target
8
Study locations

Study Summary

The study is a two part study, designed to validate safety results from the Phase 1 PP405-001 trial while also characterizing longer term safety and PK. Part 1 of the trial is the randomized controlled portion that will focus on safety and PK following 28 days of blinded treatment administration with either PP405 or vehicle control. Part 2 of the trial is an open-label extension that will validate the results of Part 1 with 3 months of treatment administration.

Conditions Studied

Interventions

  • DRUG PP405 0.05% Topical Gel
  • DRUG PP405 Topical Vehicle Gel

Study Locations (8)

California

  • California Dermatology & Clinical Research Institute - Encinitas
  • Clinical Trials Research Institute - Thousand Oaks

Texas

  • DermResearch - Austin
  • Stride Clinical Research LLC - Sugar Land

Indiana

  • Dawes Fretzin Clinical Research Group, LLC - Indianapolis

Minnesota

  • Minnesota Clinical Study Center - New Brighton

Utah

  • Jordan Valley Dermatology Center - South Jordan

Virginia

  • Virginia Clinical Research, Inc. - Norfolk

Trial Details

FieldValue
Enrollment Target 78 participants
Start Date 2024-06-05
Est. Completion 2025-10-01
Phase Phase 2

Sponsor

Pelage Pharmaceuticals

1 total trials

What the Registry Record Tells You About NCT06393452

The ClinicalTrials.gov registry entry for NCT06393452 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 78 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 160-participant average among 16 other Androgenetic Alopecia trials with a reported enrollment target (51% lower). The listed sponsor is Pelage Pharmaceuticals, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Androgenetic Alopecia appearing as the primary indexed condition, and to 2 interventions - of which PP405 0.05% Topical Gel is the first listed.

NCT06393452 reports 8 study locations spanning 6 distinct geographic areas - top geographies include California, Texas, Indiana.

Frequently Asked Questions

What is clinical trial NCT06393452 about?

NCT06393452 is a clinical study titled "Safety, Pharmacokinetics and Efficacy of PP405 in Adults With AGA". The study is a two part study, designed to validate safety results from the Phase 1 PP405-001 trial while also characterizing longer term safety and PK. Part 1 of the trial is the randomized controlled portion that will focus on safety and PK following 28 days of blinded treatment administration wit...

What is the current status of trial NCT06393452?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 78 participants. The study started on 2024-06-05. Estimated completion is 2025-10-01.

What conditions does trial NCT06393452 study?

This clinical trial studies the following conditions: Androgenetic Alopecia.

What interventions are being tested in trial NCT06393452?

The interventions under investigation include: PP405 0.05% Topical Gel (DRUG), PP405 Topical Vehicle Gel (DRUG).

Who is sponsoring clinical trial NCT06393452?

This trial is sponsored by Pelage Pharmaceuticals, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06393452 being conducted?

This trial has 8 study locations across California, Indiana, Minnesota, Texas, Utah. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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