Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT06393101 · ClinicalTrials.gov registry record · Phase 1
The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome
A Phase 1 study of Complex Regional Pain Syndrome, sponsored by University of California, San Diego.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 52
- Enrollment target
- 2
- Study locations
NCT06393101: Recruiting Phase 1 study of Complex Regional Pain Syndrome, sponsored by University of California, San Diego.
NCT06393101 is a Phase 1 study of Complex Regional Pain Syndrome that is actively recruiting participants, run by University of California, San Diego. The registered enrollment target is 52 participants, below the 254-participant average among 3 other Complex Regional Pain Syndrome trials with a reported enrollment target (80% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06393101, a Phase 1 study of Complex Regional Pain Syndrome, is actively recruiting participants, sponsored by University of California, San Diego.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 52 participants
- Enrollment target
- 2
- Study locations
Study Summary
The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how cannabinoids produce stabilized improvement in CRPS-related pain and comorbidities. The trial consisted of a pre-treatment screening period, six-week treatment period and a two-week follow-up.
Primary Outcome
Change from baseline in pain intensity and unpleasantness ratings using an 11-point Visual Analog Scale in response to heat and ongoing CRPS pain
Conditions Studied
Interventions
- DRUG BRC-002
- DRUG BRC-002 Placebo
Study Locations (2)
California
- Altman Clinical and Translational Research Institute - La Jolla
- University of California, San Diego - San Diego
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 52 participants |
| Start Date | 2024-06-01 |
| Est. Completion | 2029-06-01 |
| Phase | Phase 1 |
What NCT06393101 shows while recruiting
NCT06393101 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 52 participants, a relatively small participant target, below the 254-participant average among 3 other Complex Regional Pain Syndrome trials with a reported enrollment target (80% lower).
The record links to 1 condition, with Complex Regional Pain Syndrome appearing as the primary indexed condition, and to 2 interventions - of which BRC-002 is the first listed.
NCT06393101 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT06393101 about?
NCT06393101 is a clinical study titled "The Effects and Mechanisms of a High CBD Cannabis Extract (BRC-002) for the Treatment of Pain and Health in Complex Regional Pain Syndrome". The aim of this trial is to determine the potential effects and mechanisms of cannabinoid-induced pain relief in complex regional pain syndrome (CRPS). Multiple psychophysical approaches will be conducted in conjunction with psychological and inflammatory marker testing to determine if and how canna...
What is the current status of trial NCT06393101?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 52 participants. The study started on 2024-06-01. Estimated completion is 2029-06-01.
What conditions does trial NCT06393101 study?
This clinical trial studies the following conditions: Complex Regional Pain Syndrome.
What interventions are being tested in trial NCT06393101?
The interventions under investigation include: BRC-002 (DRUG), BRC-002 Placebo (DRUG).
Who is sponsoring clinical trial NCT06393101?
This trial is sponsored by University of California, San Diego, which has 775 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06393101 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Complex Regional Pain Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome
RECRUITING · NA
-
Safety of Intravenous Neridronic Acid in CRPS
COMPLETED · Phase 3
-
A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions
COMPLETED · Phase 4
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02630121 · 52 participants · Phase 4
Effect of Oxymetazoline Hydrochloride in Combination With Fluticasone Propionate on the Apnea Hypopnea Index (AHI) in Subject With Persistent Nasal Congestion and Mild Obstructive Sleep Apnea
- NCT03629171 · 52 participants · Phase 2
Liposome-encapsulated Daunorubicin-Cytarabine and Venetoclax in Treating Participants With Relapsed, Refractory or Untreated Acute Myeloid Leukemia
- NCT04128748 · 52 participants · Phase 1
Liposomal Cytarabine and Daunorubicin (CPX-351) and Quizartinib for the Treatment of Acute Myeloid Leukemia and High Risk Myelodysplastic Syndrome
- NCT04150497 · 52 participants · Phase 1
Phase 1/2 Study of UCART22 in Patients With Relapsed or Refractory CD22+ B-cell Acute Lymphoblastic Leukemia (BALLI-01)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI