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NCT06389578 · ClinicalTrials.gov registry record · Phase 1
A Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease
A Phase 1 study, sponsored by Amgen.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
NCT06389578: Completed Phase 1 study, sponsored by Amgen.
NCT06389578 is a Phase 1 study that has completed, run by Amgen. The registered enrollment target is 16 participants, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06389578, a Phase 1 study, has completed, sponsored by Amgen.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
Study Summary
The main goal of this study is to learn how teprotumumab will be processed in the body (Pharmacokinetics) subcutaneously and whether it is safe and tolerable after administration into adult patients with thyroid eye disease.
Primary Outcome
AUC will be evaluated from the collected PK samples.
Interventions
- DRUG Teprotumumab
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2022-07-14 |
| Est. Completion | 2023-09-12 |
| Phase | Phase 1 |
What the finished NCT06389578 record still lists
NCT06389578 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (73% lower).
The record links to 0 conditions, and to 1 intervention - of which Teprotumumab is the first listed.
NCT06389578 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06389578 about?
NCT06389578 is a clinical study titled "A Study of TEPEZZA® Treatment in Participants With Thyroid Eye Disease". The main goal of this study is to learn how teprotumumab will be processed in the body (Pharmacokinetics) subcutaneously and whether it is safe and tolerable after administration into adult patients with thyroid eye disease.
What is the current status of trial NCT06389578?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2022-07-14. Estimated completion is 2023-09-12.
What interventions are being tested in trial NCT06389578?
The interventions under investigation include: Teprotumumab (DRUG).
Who is sponsoring clinical trial NCT06389578?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06389578's enrollment target sits among peer trials
16 1786th of 2000 higher than 203 of 2,000 other Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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