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NCT06384495 · ClinicalTrials.gov registry record · NA
How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time?
A NA study, sponsored by University of Minnesota.
- Terminated
- Registry status
- NA
- Development phase
- 3
- Enrollment target
NCT06384495: Clinical Trial NA study, sponsored by University of Minnesota.
NCT06384495 is a NA study that was terminated before completion, run by University of Minnesota. The registered enrollment target is 3 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06384495, a NA study, was terminated before completion, sponsored by University of Minnesota.
- TERMINATED
- Registry status
- NA
- Development phase
- 3 participants
- Enrollment target
Study Summary
Combining cortical tDCS with behavioral interventions has been shown to have beneficial outcomes in individuals post-stroke. However, cerebellar tDCS is a fairly new approach for individuals with unilateral cortical stroke and there has not been reports of duration of effect of tDCS applied to the cerebellum in this population. Information gained from this study will serve to fill knowledge gaps on the duration of effect of cerebellar tDCS and the effects of polarity. The purpose of this study is to determine the duration of effect of ventro-lateral cerebellar transcranial direct current stimulation (tDCS) in healthy adults through cortical excitability (CE), cognitive, language and motor assessment measures. Primary aim: Compare baseline CE from left motor cortex of first dorsal interosseous (FDI) and orbicularis oris (OO) areas to CE post cerebellar tDCS at 15 minutes, 45 minutes and 75 minutes. Single-pulse and paired-pulse transcranial magnetic stimulation (TMS) will be used to measure and compare stimulus response curve (S/R curve), cortical silent period (CSP) and short-interval intracortical inhibition (SICI) in the hand area and facial area of the left primary motor cortex at each time point. Secondary aim: Compare baseline performance on cognition, motor learning and language tasks to performance at 15, 45 and 75 minutes after receiving tDCS. Digit Symbol Substitution Test (DSST), Serial Reaction Time Test (SRTT) and Lexical Decision tasks will be presented via a computer interface.
Primary Outcome
change of motor evoked potential (MEP) as reflected in EMG from 1) hand (FDI muscle) and 2) mouth (orbicularis oris muscle).following single pulse transcranial magnetic stimulation (TMS) to the primary motor cortex of varying intensities.
Interventions
- PROCEDURE REAL-A
- PROCEDURE REAL-C
- PROCEDURE SHAM
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 3 participants |
| Start Date | 2024-07-15 |
| Est. Completion | 2025-08-10 |
| Phase | NA |
Why NCT06384495 stopped before completion
NCT06384495 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 3 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (100% lower).
The record links to 0 conditions, and to 3 interventions - of which REAL-A is the first listed.
NCT06384495 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06384495 about?
NCT06384495 is a clinical study titled "How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time?". Combining cortical tDCS with behavioral interventions has been shown to have beneficial outcomes in individuals post-stroke. However, cerebellar tDCS is a fairly new approach for individuals with unilateral cortical stroke and there has not been reports of duration of effect of tDCS applied to the c...
What is the current status of trial NCT06384495?
This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2024-07-15. Estimated completion is 2025-08-10.
What interventions are being tested in trial NCT06384495?
The interventions under investigation include: REAL-A (PROCEDURE), REAL-C (PROCEDURE), SHAM (PROCEDURE).
Who is sponsoring clinical trial NCT06384495?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06384495's enrollment target sits among peer trials
3 1996th of 2000 higher than 4 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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