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NCT06384495 · ClinicalTrials.gov registry record · NA

How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time?

A NA study, sponsored by University of Minnesota.

Terminated
Registry status
NA
Development phase
3
Enrollment target

NCT06384495 is a NA study that was terminated before completion, run by University of Minnesota. The registered enrollment target is 3 participants.

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The verdict

NCT06384495, a NA study, was terminated before completion, sponsored by University of Minnesota.

TERMINATED
Registry status
NA
Development phase
3 participants
Enrollment target

Study Summary

Combining cortical tDCS with behavioral interventions has been shown to have beneficial outcomes in individuals post-stroke. However, cerebellar tDCS is a fairly new approach for individuals with unilateral cortical stroke and there has not been reports of duration of effect of tDCS applied to the cerebellum in this population. Information gained from this study will serve to fill knowledge gaps on the duration of effect of cerebellar tDCS and the effects of polarity. The purpose of this study is to determine the duration of effect of ventro-lateral cerebellar transcranial direct current stimulation (tDCS) in healthy adults through cortical excitability (CE), cognitive, language and motor assessment measures. Primary aim: Compare baseline CE from left motor cortex of first dorsal interosseous (FDI) and orbicularis oris (OO) areas to CE post cerebellar tDCS at 15 minutes, 45 minutes and 75 minutes. Single-pulse and paired-pulse transcranial magnetic stimulation (TMS) will be used to measure and compare stimulus response curve (S/R curve), cortical silent period (CSP) and short-interval intracortical inhibition (SICI) in the hand area and facial area of the left primary motor cortex at each time point. Secondary aim: Compare baseline performance on cognition, motor learning and language tasks to performance at 15, 45 and 75 minutes after receiving tDCS. Digit Symbol Substitution Test (DSST), Serial Reaction Time Test (SRTT) and Lexical Decision tasks will be presented via a computer interface.

Interventions

  • PROCEDURE REAL-A
  • PROCEDURE REAL-C
  • PROCEDURE SHAM

Trial Details

FieldValue
Enrollment Target 3 participants
Start Date 2024-07-15
Est. Completion 2025-08-10
Phase NA

Sponsor

University of Minnesota

966 total trials

What the Registry Record Tells You About NCT06384495

The ClinicalTrials.gov registry entry for NCT06384495 describes a study currently listed as terminated, categorized as NA. The registered enrollment target is 3 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Minnesota, which has 966 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which REAL-A is the first listed.

NCT06384495 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06384495 about?

NCT06384495 is a clinical study titled "How Does Cerebellar tDCS Alter Intracortical Inhibition Over Time?". Combining cortical tDCS with behavioral interventions has been shown to have beneficial outcomes in individuals post-stroke. However, cerebellar tDCS is a fairly new approach for individuals with unilateral cortical stroke and there has not been reports of duration of effect of tDCS applied to the c...

What is the current status of trial NCT06384495?

This trial is currently terminated. It is a NA study. The enrollment target is 3 participants. The study started on 2024-07-15. Estimated completion is 2025-08-10.

What interventions are being tested in trial NCT06384495?

The interventions under investigation include: REAL-A (PROCEDURE), REAL-C (PROCEDURE), SHAM (PROCEDURE).

Who is sponsoring clinical trial NCT06384495?

This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.