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NCT06382155 · ClinicalTrials.gov registry record · Phase 2

A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature

A Phase 2 study of Idiopathic Short Stature, sponsored by BioMarin Pharmaceutical.

Recruiting
Registry status
Phase 2
Development phase
100
Enrollment target
20
Study locations

NCT06382155 is a Phase 2 study of Idiopathic Short Stature that is actively recruiting participants, run by BioMarin Pharmaceutical. The registered enrollment target is 100 participants, below the 163-participant average among 4 other Idiopathic Short Stature trials with a reported enrollment target (39% lower). The trial reports 20 study locations across 8 states.

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The verdict

NCT06382155, a Phase 2 study of Idiopathic Short Stature, is actively recruiting participants, sponsored by BioMarin Pharmaceutical.

RECRUITING
Registry status
Phase 2
Development phase
100 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to evaluate i) the effect of multiple doses of vosoritide and ii) the effect of the therapeutic dose of vosoritide compared to human growth hormone (hGH)(hGH; only in the United States), in children with idiopathic short stature (ISS).

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Vosoritide Injection
  • DRUG Human Growth Hormone

Study Locations (20)

California

  • Consano Clinical Research, LLC - California City
  • Rady Children's Hospital - San Diego - California City
  • Children's Hospital of Orange County Main Campus - Orange - California City
  • Children's Hospital Los Angeles - Los Angeles
  • Children's Hospital Oakland Research Institute - Oakland
  • Center Of Excellence in Diabetes and Endocrinology - Sacramento
  • Lundquist Institute for Biomedical Innovation (LA BioMed) - Torrance

Florida

  • Nemours Children's Specialty Care Jacksonville - Jacksonville
  • Nicklaus Children's Hospital - Miami
  • Optimal Research Sites - Orange City
  • Nemours Children's Health System - Corporate Headquarters - Pensacola

Idaho

  • St. Luke's Children's Endocrinology - Boise
  • Rocky Mountain Clinical Research - Idaho Falls - Idaho Falls

Kentucky

  • Kentucky Children's Hospital - Lexington
  • University of Louisville School of Medicine - Louisville

Louisiana

  • Velocity Clinical Research - MedPharmics - Lafayette - Lafayette
  • Ochsner Health Center for Children - New Orleans - New Orleans

District of Columbia

  • The Children's National Research Institute - Washington D.C.

Georgia

  • Centricity Research - Columbus

Iowa

  • University of Iowa Stead Family Children's Hospital - Iowa City

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2024-10-21
Est. Completion 2036-12
Phase Phase 2

Sponsor

BioMarin Pharmaceutical

80 total trials

What the Registry Record Tells You About NCT06382155

The ClinicalTrials.gov registry entry for NCT06382155 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 100 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 163-participant average among 4 other Idiopathic Short Stature trials with a reported enrollment target (39% lower). The listed sponsor is BioMarin Pharmaceutical, which has 80 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Idiopathic Short Stature appearing as the primary indexed condition, and to 3 interventions - of which Placebo is the first listed.

NCT06382155 reports 20 study locations spanning 8 distinct geographic areas - top geographies include California, Florida, Idaho.

Frequently Asked Questions

What is clinical trial NCT06382155 about?

NCT06382155 is a clinical study titled "A Phase 2 Study of Vosoritide in Children With Idiopathic Short Stature". The purpose of this study is to evaluate i) the effect of multiple doses of vosoritide and ii) the effect of the therapeutic dose of vosoritide compared to human growth hormone (hGH)(hGH; only in the United States), in children with idiopathic short stature (ISS).

What is the current status of trial NCT06382155?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 100 participants. The study started on 2024-10-21. Estimated completion is 2036-12.

What conditions does trial NCT06382155 study?

This clinical trial studies the following conditions: Idiopathic Short Stature.

What interventions are being tested in trial NCT06382155?

The interventions under investigation include: Placebo (DRUG), Vosoritide Injection (DRUG), Human Growth Hormone (DRUG).

Who is sponsoring clinical trial NCT06382155?

This trial is sponsored by BioMarin Pharmaceutical, which has 80 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06382155 being conducted?

This trial has 20 study locations across California, District of Columbia, Florida, Georgia, Idaho. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.