Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT06373289 · ClinicalTrials.gov registry record · NA

Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants

A NA study, sponsored by University of Alabama at Birmingham.

Recruiting
Registry status
NA
Development phase
39
Enrollment target

NCT06373289: Recruiting NA study, sponsored by University of Alabama at Birmingham.

NCT06373289 is a NA study that is actively recruiting participants, run by University of Alabama at Birmingham. The registered enrollment target is 39 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT06373289, a NA study, is actively recruiting participants, sponsored by University of Alabama at Birmingham.

RECRUITING
Registry status
NA
Development phase
39 participants
Enrollment target

Study Summary

Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most appropriate oxygen targets that will improve outcomes in infants with this condition. This clinical trial will determine whether using different amounts of oxygen improve outcomes in infants with this disease.

Primary Outcome

The average duration of time (in seconds) an infant's oxygen saturation decrease below 80%.

Interventions

  • DEVICE higher oxygen saturation target using Nellcor pulse oximetry sensors
  • DEVICE lower oxygen saturation target using Nellcor pulse oximetry sensors

Trial Details

FieldValue
Enrollment Target 39 participants
Start Date 2026-07-15
Est. Completion 2029-12-01
Phase NA
University of Alabama at Birmingham

1,160 total trials

What NCT06373289 shows while recruiting

NCT06373289 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 39 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (97% lower).

The record links to 0 conditions, and to 2 interventions - of which higher oxygen saturation target using Nellcor pulse oximetry sensors is the first listed.

NCT06373289 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT06373289 about?

NCT06373289 is a clinical study titled "Pulmonary Hypertension and Oxygen Saturation Targeting in Preterm Infants". Around 50% of infants born extremely preterm develop a chronic lung disease known as bronchopulmonary dysplasia of which some infants will also develop pulmonary hypertension of which 50% of children will die before the age of 2. Physicians are currently limited in their ability to select the most a...

What is the current status of trial NCT06373289?

This trial is currently recruiting. It is a NA study. The enrollment target is 39 participants. The study started on 2026-07-15. Estimated completion is 2029-12-01.

What interventions are being tested in trial NCT06373289?

The interventions under investigation include: higher oxygen saturation target using Nellcor pulse oximetry sensors (DEVICE), lower oxygen saturation target using Nellcor pulse oximetry sensors (DEVICE).

Who is sponsoring clinical trial NCT06373289?

This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT06373289's enrollment target sits among peer trials

39 1536th of 2000 higher than 463 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT03465592 · 39 participants · Phase 1

    Trial of Nivolumab Following Partially Human Leukocyte Antigen (HLA) Mismatched BMT in Children & Adults With Sarcoma

  • NCT03961776 · 39 participants

    Monitoring Treatment Response With On-board DWI During Neo-adjuvant Chemo-radiation for Rectal Cancer Using Magnetic Resonance-guided-radiotherapy Systems

  • NCT04050280 · 39 participants · Phase 2

    CLAG-GO for Patients With Persistent, Relapsed or Refractory AML

  • NCT04190862 · 39 participants · Phase 1

    E-CEL UVEC as an Adjunct Cell Therapy for Treatment of Anal Fistulas

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT06373289, the US trial registry maintained by the National Library of Medicine. NCT06373289 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.