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NCT06364657 · ClinicalTrials.gov registry record
Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye
A clinical trial, sponsored by Johns Hopkins University.
- Terminated
- Registry status
- 13
- Enrollment target
NCT06364657: Clinical Trial study, sponsored by Johns Hopkins University.
NCT06364657 is a clinical trial that was terminated before completion, run by Johns Hopkins University. The registered enrollment target is 13 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06364657 was terminated before completion, sponsored by Johns Hopkins University.
- TERMINATED
- Registry status
- 13 participants
- Enrollment target
Study Summary
In this study the investigators plan to enroll three groups of patients: non-Sjogren's dry eye, Sjogren's dry eye and controls. The study has the following primary goals: 1. To determine whether dry eye is associated with reduced corneal sensation 2. To determine whether reduced corneal sensation is due to the severity of the dry eye, the type of dry eye (primarily aqueous deficient versus primarily evaporative) or entirely related to the presence of Sjogren's 3. To determine whether corneal sensation is associated with ocular or systemic pain symptoms Additionally, the study aims to compare the novel corneal esthesiometer measurements to confocal biomicroscopy findings in determining neurotrophic keratitis (NK) and assess correlations between corneal sensation.
Primary Outcome
Measuring epithelial staining score and epithelial thickness map using anterior segment Optical coherence tomography (OCT)
Interventions
- DIAGNOSTIC_TEST Eye Exam
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 13 participants |
| Start Date | 2024-07-01 |
| Est. Completion | 2024-12-19 |
Why NCT06364657 stopped before completion
NCT06364657 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 13 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Eye Exam is the first listed.
NCT06364657 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06364657 about?
NCT06364657 is a clinical study titled "Differences in Corneal Structure and Function in Patients With Sjogrens vs. Non-Sjogrens Dry Eye". In this study the investigators plan to enroll three groups of patients: non-Sjogren's dry eye, Sjogren's dry eye and controls. The study has the following primary goals: 1. To determine whether dry eye is associated with reduced corneal sensation 2. To determine whether reduced corneal sensation i...
What is the current status of trial NCT06364657?
This trial is currently terminated. The enrollment target is 13 participants. The study started on 2024-07-01. Estimated completion is 2024-12-19.
What interventions are being tested in trial NCT06364657?
The interventions under investigation include: Eye Exam (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT06364657?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
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