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NCT06351540 · ClinicalTrials.gov registry record · Phase 1

Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance

A Phase 1 study, sponsored by Johns Hopkins University.

Not yet
Registry status
Phase 1
Development phase
40
Enrollment target

NCT06351540: Clinical Trial Phase 1 study, sponsored by Johns Hopkins University.

NCT06351540 is a Phase 1 study that has not yet begun recruiting, run by Johns Hopkins University. The registered enrollment target is 40 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT06351540, a Phase 1 study, has not yet begun recruiting, sponsored by Johns Hopkins University.

NOT YET RECRUITING
Registry status
Phase 1
Development phase
40 participants
Enrollment target

Study Summary

The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this detection threshold, and to examine how the oculomotor index corresponds to a measure of sustained attention. A double-blind, placebo-controlled, within-subjects crossover design will be used to examine the dose-effects of THC (0, 5mg, 30mg) on oculomotor performance tasks and a sustained attention task in frequent and infrequent cannabis users. Results from the study will advance the investigators' understanding of the effect of THC and cannabis use frequency on oculomotor function and sustained attention, and will directly inform the validity of the investigators' oculomotor platform for identifying acute THC- induced impairment in frequent and infrequent users.

Interventions

  • DRUG Cannabis

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-08-01
Est. Completion 2027-07-01
Phase Phase 1

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT06351540

The ClinicalTrials.gov registry entry for NCT06351540 describes a study currently listed as not yet recruiting, categorized as Phase 1. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Cannabis is the first listed.

NCT06351540 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT06351540 about?

NCT06351540 is a clinical study titled "Examining the Role of Tolerance on Dose-dependent Effects of Acute THC on Oculomotor and Cognitive Performance". The purpose of this research is to determine the extent to which oculomotor function accurately detects THC-impairment, if cannabis use experience impacts this detection threshold, and to examine how the oculomotor index corresponds to a measure of sustained attention. A double-blind, placebo-contro...

What is the current status of trial NCT06351540?

This trial is currently not yet recruiting. It is a Phase 1 study. The enrollment target is 40 participants. The study started on 2026-08-01. Estimated completion is 2027-07-01.

What interventions are being tested in trial NCT06351540?

The interventions under investigation include: Cannabis (DRUG).

Who is sponsoring clinical trial NCT06351540?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.