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NCT06351293 · ClinicalTrials.gov registry record · NA
A Comparative Analysis of Two Hyaluronic Acid Fillers for Nasolabial Fold Correction
A NA study, sponsored by Galderma R&D.
- Completed
- Registry status
- NA
- Development phase
- 15
- Enrollment target
NCT06351293: Completed NA study, sponsored by Galderma R&D.
NCT06351293 is a NA study that has completed, run by Galderma R&D. The registered enrollment target is 15 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06351293, a NA study, has completed, sponsored by Galderma R&D.
- COMPLETED
- Registry status
- NA
- Development phase
- 15 participants
- Enrollment target
Study Summary
This is a randomized, split-face, subject-blinded, comparative study. Subjects will receive initial treatment with Defyne on one of the NLFs and with RHA3 on the other based on the pre-determined randomization. 4 weeks after the initial treatment, subjects will receive optional touch-up on one side or both sides at the Investigator's discretion for optimal correction. Subjects to return to the site at Month 3, 6, and 12 for follow-ups.
Primary Outcome
A single ultrasound assessment will be taken on each subject's left and right NLF, at neutral expression and at maximum smiling, in photo and video format. The placement of the ultrasound probe will be on the NLF, at the half-way point between nasal ala and oral commissure. Ultrasound assessments will be performed using an 18 MHz GE Venue Fit, a 20 MHz GE, and a 70 MHz Vevo MD ultrasonic transducer interfaced to a system. The probe will have a standard setting of gain, depth, and velocity scale
Interventions
- DEVICE Defyne Treatment in Nasolabial Fold
- DEVICE RHA3 Treatment in Nasolabial Fold
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2024-02-21 |
| Est. Completion | 2025-04-30 |
| Phase | NA |
What the finished NCT06351293 record still lists
NCT06351293 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (99% lower).
The record links to 0 conditions, and to 2 interventions - of which Defyne Treatment in Nasolabial Fold is the first listed.
NCT06351293 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06351293 about?
NCT06351293 is a clinical study titled "A Comparative Analysis of Two Hyaluronic Acid Fillers for Nasolabial Fold Correction". This is a randomized, split-face, subject-blinded, comparative study. Subjects will receive initial treatment with Defyne on one of the NLFs and with RHA3 on the other based on the pre-determined randomization. 4 weeks after the initial treatment, subjects will receive optional touch-up on one side...
What is the current status of trial NCT06351293?
This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2024-02-21. Estimated completion is 2025-04-30.
What interventions are being tested in trial NCT06351293?
The interventions under investigation include: Defyne Treatment in Nasolabial Fold (DEVICE), RHA3 Treatment in Nasolabial Fold (DEVICE).
Who is sponsoring clinical trial NCT06351293?
This trial is sponsored by Galderma R&D, which has 158 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06351293's enrollment target sits among peer trials
15 1881st of 2000 higher than 92 of 2,000 other NA trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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