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NCT06335212 · ClinicalTrials.gov registry record
Peripheral Defocus Profile of Multifocal Minus Contact Lenses
A clinical trial, sponsored by State University of New York College of Optometry.
- Completed
- Registry status
- 19
- Enrollment target
NCT06335212: Completed study, sponsored by State University of New York College of Optometry.
NCT06335212 is a clinical trial that has completed, run by State University of New York College of Optometry. The registered enrollment target is 19 participants. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06335212 has completed, sponsored by State University of New York College of Optometry.
- COMPLETED
- Registry status
- 19 participants
- Enrollment target
Study Summary
Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia progression and axial elongation. As such, multifocal soft contact lenses (MFCLs) have been utilized for myopia control in school-aged children, with variable efficacies. One potential explanation is that the actual peripheral myopic defocus an eye experiences during MFCL wear may not be identical to the Add power and not sufficient to reduce myopia progression. Our study investigated and compared the peripheral power profiles of myopic eyes when they were uncorrected and wore single vision contact lenses (SVCLs) and MFCLs of different Add powers. Methods: Subjects with -1.00 D to -10.00 D of myopia (SE, determined with manifest refraction) were custom fit with both single vision (SV) and MFCLs (+2.00 and +4.00 D Add; provided by Specialeyes) in both eyes. These Specialeyes MFCLs had an aspheric design with a standard total optical zone of 8.0mm. Cycloplegic central autorefraction was conducted with both Grand Seiko WAM-5500 open-field auto-refractor (Grand Seiko Co Ltd) and OPD OPD-Scan III Wavefront Aberrometer (Marco) on the subjects in the following conditions: (1) no CLs, (2) SVCLs, (3) MFCLs (+2.00D Add), and (4) MFCLs (+4.00D Add). Relative peripheral power profiles were measured using the OPD under the same 4 conditions after cycloplegia. Data in the right eye was used for analysis.
Primary Outcome
Relative pupil limited optical power profile
Interventions
- DEVICE Single vision and multifocal contact lenses
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 19 participants |
| Start Date | 2019-06-01 |
| Est. Completion | 2019-08-05 |
What the finished NCT06335212 record still lists
NCT06335212 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 19 participants, a relatively small participant target.
The record links to 0 conditions, and to 1 intervention - of which Single vision and multifocal contact lenses is the first listed.
NCT06335212 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06335212 about?
NCT06335212 is a clinical study titled "Peripheral Defocus Profile of Multifocal Minus Contact Lenses". Purpose: Numerous studies have proven that emmetropization in young animals including humans is regulated by visual input. It has long been hypothesized that peripheral myopic defocus may act as a stop signal to reduce myopia progression and axial elongation. As such, multifocal soft contact lenses ...
What is the current status of trial NCT06335212?
This trial is currently completed. The enrollment target is 19 participants. The study started on 2019-06-01. Estimated completion is 2019-08-05.
What interventions are being tested in trial NCT06335212?
The interventions under investigation include: Single vision and multifocal contact lenses (DEVICE).
Who is sponsoring clinical trial NCT06335212?
This trial is sponsored by State University of New York College of Optometry, which has 14 total clinical trials registered on ClinicalTrials.gov.
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