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NCT06330545 · ClinicalTrials.gov registry record · NA
Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release
A NA study of Dupuytren Contracture, sponsored by Dartmouth-Hitchcock Medical Center.
- Recruiting
- Registry status
- NA
- Development phase
- 95
- Enrollment target
- 1
- Study location
NCT06330545: Recruiting NA study of Dupuytren Contracture, sponsored by Dartmouth-Hitchcock Medical Center.
NCT06330545 is a NA study of Dupuytren Contracture that is actively recruiting participants, run by Dartmouth-Hitchcock Medical Center. The registered enrollment target is 95 participants, above the 75-participant average among 4 other Dupuytren Contracture trials with a reported enrollment target (27% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06330545, a NA study of Dupuytren Contracture, is actively recruiting participants, sponsored by Dartmouth-Hitchcock Medical Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 95 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this study is to learn about preventing recurrence of Dupuytren's Contracture. The main question it aims to answer are: • Does targeted radiation therapy decrease recurrence of Dupuytren's contracture after treatment with Collagenase Clostridium Histolyticum? Participants will undergo: * Release of Dupuytren's Contracture after Collagenase Clostridium Histolyticum injection * Daily radiation therapy treatment for 5 days followed by 6-8 week rest period and then another course of 5 days of radiation therapy
Primary Outcome
Recurrence defined as \> 20 degrees worsening of contracture relative to within 14 days from CCH injection or the need for medical/surgical intervention to correct the new or worsening symptomatic contracture. The investigators will measure the contracture using the table top test in which patients their press hand with best of their ability. We will use a goniometer on dorsal surface of hand while performing table top test to measure PIP and MCP joints.
Conditions Studied
Interventions
- RADIATION Radiation therapy
Study Locations (1)
New Hampshire
- Dartmouth Hitchcock - Lebanon
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 95 participants |
| Start Date | 2024-09-16 |
| Est. Completion | 2032-04 |
| Phase | NA |
What NCT06330545 shows while recruiting
NCT06330545 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 95 participants, a relatively small participant target, above the 75-participant average among 4 other Dupuytren Contracture trials with a reported enrollment target (27% higher).
The record links to 1 condition, with Dupuytren Contracture appearing as the primary indexed condition, and to 1 intervention - of which Radiation therapy is the first listed.
NCT06330545 reports a single indexed study location in New Hampshire.
Frequently Asked Questions
What is clinical trial NCT06330545 about?
NCT06330545 is a clinical study titled "Radiation Therapy for Dupuytren's Contracture Following Non-Surgical Release". The goal of this study is to learn about preventing recurrence of Dupuytren's Contracture. The main question it aims to answer are: • Does targeted radiation therapy decrease recurrence of Dupuytren's contracture after treatment with Collagenase Clostridium Histolyticum? Participants will undergo:...
What is the current status of trial NCT06330545?
This trial is currently recruiting. It is a NA study. The enrollment target is 95 participants. The study started on 2024-09-16. Estimated completion is 2032-04.
What conditions does trial NCT06330545 study?
This clinical trial studies the following conditions: Dupuytren Contracture.
What interventions are being tested in trial NCT06330545?
The interventions under investigation include: Radiation therapy (RADIATION).
Who is sponsoring clinical trial NCT06330545?
This trial is sponsored by Dartmouth-Hitchcock Medical Center, which has 427 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06330545 being conducted?
This trial has 1 study location across New Hampshire. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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