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NCT06321601 · ClinicalTrials.gov registry record · Phase 3
Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.
A Phase 3 study of Vasculitis, sponsored by Amgen.
- Recruiting
- Registry status
- Phase 3
- Development phase
- 20
- Enrollment target
- 20
- Study locations
NCT06321601: Recruiting Phase 3 study of Vasculitis, sponsored by Amgen.
NCT06321601 is a Phase 3 study of Vasculitis that is actively recruiting participants, run by Amgen. The registered enrollment target is 20 participants, below the 27,317-participant average among 11 other Vasculitis trials with a reported enrollment target (100% lower). The trial reports 20 study locations across 11 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06321601, a Phase 3 study of Vasculitis, is actively recruiting participants, sponsored by Amgen.
- RECRUITING
- Registry status
- Phase 3
- Development phase
- 20 participants
- Enrollment target
- 20
- Study locations
Study Summary
The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV.
Conditions Studied
Interventions
- DRUG Avacopan
Study Locations (20)
Other
- Universitair Ziekenhuis Gent - Ghent
- Universitair Ziekenhuis Leuven - Gasthuisberg - Leuven
- Vseobecna fakultni nemocnice v Praze - Prague
- Fakultni nemocnice v Motole - Prague
- Centre Hospitalier Universitaire de Bordeaux - Hopital Pellegrin - Bordeaux
- Hospices Civils de Lyon Hopital Femme Mere Enfant - Bron
- Hopital Necker Enfants Malades - Paris
North Carolina
- University of North Carolina - Chapel Hill
- Wake Forest University Health Sciences - Charlotte
Ohio
- Akron Childrens Hospital - Akron
- Cleveland Clinic Foundation - Cleveland
Alberta
- Alberta Childrens Hospital - Calgary
- Stollery Childrens Hospital - Edmonton
Georgia
- Emory University - Atlanta
Indiana
- Riley Hospital for Children - Indianapolis
Minnesota
- University of Minnesota Masonic Childrens Hospital Discovery Clinic - Minneapolis
New York
- Cohen Children Medical Center - Lake Success
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2024-10-22 |
| Est. Completion | 2028-09-26 |
| Phase | Phase 3 |
What NCT06321601 shows while recruiting
NCT06321601 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 27,317-participant average among 11 other Vasculitis trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Vasculitis appearing as the primary indexed condition, and to 1 intervention - of which Avacopan is the first listed.
NCT06321601 names 20 study sites across 11 states, led by Other, North Carolina, Ohio.
Frequently Asked Questions
What is clinical trial NCT06321601 about?
NCT06321601 is a clinical study titled "Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.". The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV.
What is the current status of trial NCT06321601?
This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 20 participants. The study started on 2024-10-22. Estimated completion is 2028-09-26.
What conditions does trial NCT06321601 study?
This clinical trial studies the following conditions: Vasculitis.
What interventions are being tested in trial NCT06321601?
The interventions under investigation include: Avacopan (DRUG).
Who is sponsoring clinical trial NCT06321601?
This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06321601 being conducted?
This trial has 20 study locations across Georgia, Indiana, Minnesota, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Vasculitis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06321601's enrollment target sits among peer trials
20 9th of 11 higher than 3 of 11 other Vasculitis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Vasculitis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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