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NCT06321601 · ClinicalTrials.gov registry record · Phase 3

Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.

A Phase 3 study of Vasculitis, sponsored by Amgen.

Recruiting
Registry status
Phase 3
Development phase
20
Enrollment target
20
Study locations

NCT06321601 is a Phase 3 study of Vasculitis that is actively recruiting participants, run by Amgen. The registered enrollment target is 20 participants, below the 27,317-participant average among 11 other Vasculitis trials with a reported enrollment target (100% lower). The trial reports 20 study locations across 11 states.

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The verdict

NCT06321601, a Phase 3 study of Vasculitis, is actively recruiting participants, sponsored by Amgen.

RECRUITING
Registry status
Phase 3
Development phase
20 participants
Enrollment target
20
Study locations

Study Summary

The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV.

Conditions Studied

Interventions

  • DRUG Avacopan

Study Locations (20)

Other

  • Universitair Ziekenhuis Gent - Ghent
  • Universitair Ziekenhuis Leuven - Gasthuisberg - Leuven
  • Vseobecna fakultni nemocnice v Praze - Prague
  • Fakultni nemocnice v Motole - Prague
  • Centre Hospitalier Universitaire de Bordeaux - Hopital Pellegrin - Bordeaux
  • Hospices Civils de Lyon Hopital Femme Mere Enfant - Bron
  • Hopital Necker Enfants Malades - Paris

North Carolina

  • University of North Carolina - Chapel Hill
  • Wake Forest University Health Sciences - Charlotte

Ohio

  • Akron Childrens Hospital - Akron
  • Cleveland Clinic Foundation - Cleveland

Alberta

  • Alberta Childrens Hospital - Calgary
  • Stollery Childrens Hospital - Edmonton

Georgia

  • Emory University - Atlanta

Indiana

  • Riley Hospital for Children - Indianapolis

Minnesota

  • University of Minnesota Masonic Childrens Hospital Discovery Clinic - Minneapolis

New York

  • Cohen Children Medical Center - Lake Success

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2024-10-22
Est. Completion 2028-09-26
Phase Phase 3

Sponsor

Amgen

558 total trials

What the Registry Record Tells You About NCT06321601

The ClinicalTrials.gov registry entry for NCT06321601 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 27,317-participant average among 11 other Vasculitis trials with a reported enrollment target (100% lower). The listed sponsor is Amgen, which has 558 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Vasculitis appearing as the primary indexed condition, and to 1 intervention - of which Avacopan is the first listed.

NCT06321601 reports 20 study locations spanning 11 distinct geographic areas - top geographies include Other, North Carolina, Ohio.

Frequently Asked Questions

What is clinical trial NCT06321601 about?

NCT06321601 is a clinical study titled "Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.". The main objective of this study is to explore the efficacy of avacopan in participants affected by AAV.

What is the current status of trial NCT06321601?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 20 participants. The study started on 2024-10-22. Estimated completion is 2028-09-26.

What conditions does trial NCT06321601 study?

This clinical trial studies the following conditions: Vasculitis.

What interventions are being tested in trial NCT06321601?

The interventions under investigation include: Avacopan (DRUG).

Who is sponsoring clinical trial NCT06321601?

This trial is sponsored by Amgen, which has 558 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06321601 being conducted?

This trial has 20 study locations across Georgia, Indiana, Minnesota, New York, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.