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NCT06312657 · ClinicalTrials.gov registry record · Early Phase 1
Behavioral Effects of Drugs Inpatient 44 Neurobehavioral Mechanisms of Opioid Choice
A Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
- Terminated
- Registry status
- Early Phase 1
- Development phase
- 2
- Enrollment target
NCT06312657: Clinical Trial Early Phase 1 study, sponsored by Joshua A. Lile, Ph.D..
NCT06312657 is a Early Phase 1 study that was terminated before completion, run by Joshua A. Lile, Ph.D.. The registered enrollment target is 2 participants, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06312657, a Early Phase 1 study, was terminated before completion, sponsored by Joshua A. Lile, Ph.D..
- TERMINATED
- Registry status
- Early Phase 1
- Development phase
- 2 participants
- Enrollment target
Study Summary
The objective of this protocol is to use probabilistic choice tasks to determine the impact of withdrawal and drug cues on decision-making in individuals with opioid use disorder and physical opioid dependence.
Primary Outcome
Proportion of high probability choices. Subjects can choose between two options, one of which is rewarded at a higher probability than the other at a ratio of 6:1. The number of trials varied, so a proportion of total trials is reported.
Interventions
- DRUG Remifentanil
- BEHAVIORAL Money
- BEHAVIORAL Drug Cue
- DRUG Withdrawal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 2 participants |
| Start Date | 2023-03-01 |
| Est. Completion | 2025-03-28 |
| Phase | Early Phase 1 |
Why NCT06312657 stopped before completion
NCT06312657 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 2 participants, a relatively small participant target, below the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (96% lower).
The record links to 0 conditions, and to 4 interventions - of which Remifentanil is the first listed.
NCT06312657 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT06312657 about?
NCT06312657 is a clinical study titled "Behavioral Effects of Drugs Inpatient 44 Neurobehavioral Mechanisms of Opioid Choice". The objective of this protocol is to use probabilistic choice tasks to determine the impact of withdrawal and drug cues on decision-making in individuals with opioid use disorder and physical opioid dependence.
What is the current status of trial NCT06312657?
This trial is currently terminated. It is a Early Phase 1 study. The enrollment target is 2 participants. The study started on 2023-03-01. Estimated completion is 2025-03-28.
What interventions are being tested in trial NCT06312657?
The interventions under investigation include: Remifentanil (DRUG), Money (BEHAVIORAL), Drug Cue (BEHAVIORAL), Withdrawal (DRUG).
Who is sponsoring clinical trial NCT06312657?
This trial is sponsored by Joshua A. Lile, Ph.D., which has 7 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT06312657's enrollment target sits among peer trials
2 1973rd of 2000 higher than 16 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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